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Wave Life Sciences
WVE

Overview Fund Activity

176 hedge funds and large institutions have $903M invested in Wave Life Sciences in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 84 increasing their positions, 39 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
176
Holders Change
-19
Holders Change %
-9.74%
% of All Funds
2.36%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
24
Increased
84
Reduced
39
Closed
40
Calls
$3.37M
Puts
$306K
Net Calls
+$3.06M
Net Calls Change
+$13K

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$16.3M
2
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$6.92M
3
Loomis, Sayles & Company
Loomis, Sayles & Company
Massachusetts
+$5.58M
4
SC
Stempoint Capital
New York
+$5.27M
5
BlackRock
BlackRock
New York
+$4.91M

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
-$9.92M
2
SCM
Silverarc Capital Management
Massachusetts
-$8.49M
3
KCM
Kynam Capital Management
New Jersey
-$2.21M
4
TI
Trexquant Investment
Connecticut
-$1.81M
5
EI
EAM Investors
California
-$1.73M
Name Holding Trade Value Shares
Change 		Shares
Change %
SPS
51
Susquehanna Portfolio Strategies
Pennsylvania
$1.85M +$1.76M +270,758 +1,890%
DFCM
52
Dark Forest Capital Management
Puerto Rico
$1.82M +$543K +83,549 +42%
CCM
53
Cinctive Capital Management
New York
$1.81M +$1.81M +277,764 New
D.E. Shaw & Co
54
D.E. Shaw & Co
New York
$1.76M +$1.07M +164,920 +155%
Macquarie Group
55
Macquarie Group
Australia
$1.74M -$35.6K -5,470 -2%
NL
56
Nuveen LLC
North Carolina
$1.62M +$1.3M +199,266 +397%
FMI
57
F/M Investments
District of Columbia
$1.58M +$21.2K +3,259 +1%
Two Sigma Investments
58
Two Sigma Investments
New York
$1.58M +$9.45K +1,453 +0.6%
Susquehanna International Group
59
Susquehanna International Group
Pennsylvania
$1.46M +$698K +107,337 +92%
Swiss National Bank
60
Swiss National Bank
Switzerland
$1.33M +$85.8K +13,200 +7%
TD Asset Management
61
TD Asset Management
Ontario, Canada
$1.17M +$164K +25,200 +16%
TC
62
TwinBeech Capital
New York
$1.06M -$1.51M -232,303 -59%
Manulife (Manufacturers Life Insurance)
63
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.06M +$51.4K +7,913 +5%
RhumbLine Advisers
64
RhumbLine Advisers
Massachusetts
$1.06M +$194K +29,899 +23%
IC
65
Ikarian Capital
Texas
$1.05M +$1.05M +161,137 New
New York State Common Retirement Fund
66
New York State Common Retirement Fund
New York
$978K – – –
Mirae Asset Global ETFs Holdings
67
Mirae Asset Global ETFs Holdings
Hong Kong
$945K +$572K +87,959 +153%
PFM
68
Privium Fund Management
Netherlands
$884K +$143K +22,000 +19%
BFM
69
Boothbay Fund Management
New York
$864K +$560K +86,145 +184%
Wells Fargo
70
Wells Fargo
California
$810K -$639K -98,295 -44%
JJBC
71
James J. Burns & Company
New York
$792K – – –
SI
72
Sofinnova Investments
California
$766K +$766K +117,903 New
Invesco
73
Invesco
Georgia
$747K +$235K +36,079 +46%
ACM
74
ADAR1 Capital Management
Texas
$746K +$596K +91,714 +397%
Legal & General Group
75
Legal & General Group
United Kingdom
$663K -$90.8K -13,962 -12%
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