Two Sigma Investments
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Two Sigma Investments’s Wave Life Sciences WVE Stock Holding History

Two Sigma Investments’s Portfolio WVE Stock Details WVE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$13.6M Buy
1,878,115
+1,128,667
+151% +$14.7M 0.01% 1204
2025
Q4 		$12.7M Buy
749,448
+186,444
+33% +$1.89M 0.02% 973
2025
Q3 		$4.12M Buy
563,004
+319,837
+132% +$2.59M 0.01% 1602
2025
Q2 		$1.58M Buy
243,167
+1,453
+0.6% +$9.6K ﹤0.01% 1984
2025
Q1 		$1.95M Sell
241,714
-149,906
-38% -$1.64M ﹤0.01% 1754
2024
Q4 		$4.84M Buy
391,620
+265,437
+210% +$3.54M 0.01% 1126
2024
Q3 		$1.03M Buy
126,183
+1,504
+1% +$8.99K ﹤0.01% 2100
2024
Q2 		$622K Sell
124,679
-292,046
-70% -$1.67M ﹤0.01% 2258
2024
Q1 		$2.57M Buy
416,725
+390,182
+1,470% +$1.95M 0.01% 1319
2023
Q4 		$134K Buy
+26,543
New +$142K ﹤0.01% 2911
2023
Q1 		– Sell
-168,927
Closed -$1.18M – 3231
2022
Q4 		$1.18M Buy
168,927
+105,261
+165% +$485K ﹤0.01% 1622
2022
Q3 		$230K Buy
+63,666
New +$211K ﹤0.01% 2058
2022
Q1 		– Sell
-37,898
Closed -$119K – 4487
2021
Q4 		$119K Buy
+37,898
New +$157K ﹤0.01% 4030
2021
Q3 		– Sell
-52,500
Closed -$350K – 4779
2021
Q2 		$350K Buy
52,500
+35,900
+216% +$235K ﹤0.01% 3380
2021
Q1 		$93K Buy
16,600
+3,500
+27% +$33.6K ﹤0.01% 3710
2020
Q4 		$103K Buy
+13,100
New +$110K ﹤0.01% 3211
2018
Q1 		– Sell
-23,601
Closed -$828K – 3563
2017
Q4 		$828K Buy
+23,601
New +$688K ﹤0.01% 2089

Other funds holding WVE

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
GP
GSK plc London $599M AUM
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
MC
Maverick Capital Dallas, Texas $8.67B AUM 48.76% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
6CM
683 Capital Management New York $1.92B AUM 85.52% 1-Year Est. Return
Primecap Management
Primecap Management Pasadena, California $127B AUM 44.11% 1-Year Est. Return

Two Sigma Investments's WVE Position: Q1 2026 in Review

Two Sigma Investments increased its Wave Life Sciences (WVE) stake by 151% in Q1 2026, buying an estimated $14.7M and bringing the position to 1,878,115 shares worth $13.6M. The position accounts for 0.01% of the portfolio, ranked #1204.

Two Sigma Investments first reported a position in WVE in Q4 2017 and has held it in 17 quarters since. 230 funds tracked by Wall St. Rank hold WVE as of Q1 2026.

  • Two Sigma Investments held 1,878,115 shares of Wave Life Sciences worth $13.6M as of Q1 2026.
  • Two Sigma Investments bought 1,128,667 Wave Life Sciences shares in Q1 2026, an estimated $14.7M.
  • Wave Life Sciences made up 0.01% of Two Sigma Investments's portfolio in Q1 2026, its #1204 holding.
  • Two Sigma Investments first reported a position in Wave Life Sciences in Q4 2017 and has held it in 17 quarters since.
  • 230 funds tracked by Wall St. Rank held Wave Life Sciences as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.