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Wave Life Sciences

196 hedge funds and large institutions have $1.06B invested in Wave Life Sciences in 2025 Q1 according to their latest regulatory filings, with 33 funds opening new positions, 83 increasing their positions, 52 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

164% more call options, than puts

Call options by funds: $4.91M | Put options by funds: $1.86M

65% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 20

60% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 52

7% more funds holding

Funds holding: 183196 (+13)

1.28% more ownership

Funds ownership: 84.33%85.6% (+1.3%)

0% more funds holding in top 10

Funds holding in top 10: 44 (0)

33% less capital invested

Capital invested by funds: $1.59B → $1.06B (-$529M)

Holders
196
Holders Change
+13
Holders Change %
+7.1%
% of All Funds
2.63%
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.05%
New
33
Increased
83
Reduced
52
Closed
20
Calls
$4.91M
Puts
$1.86M
Net Calls
+$3.05M
Net Calls Change
-$854K
Name Holding Trade Value Shares
Change
Change in
Stake
SCM
26
Silverarc Capital Management
Massachusetts
$8.49M +$4.83M +441,477 +73%
PCH
27
Polar Capital Holdings
United Kingdom
$8.11M +$38.3K +3,500 +0.4%
Northern Trust
28
Northern Trust
Illinois
$7.85M +$109K +9,995 +1%
Charles Schwab
29
Charles Schwab
California
$7.78M +$532K +48,656 +5%
RI
30
RTW Investments
New York
$7.27M
Voloridge Investment Management
31
Voloridge Investment Management
Florida
$6.23M -$822K -75,123 -9%
Goldman Sachs
32
Goldman Sachs
New York
$4.51M +$226K +20,624 +4%
Bank of America
33
Bank of America
North Carolina
$4.32M +$1.09M +99,369 +23%
Schroder Investment Management Group
34
Schroder Investment Management Group
United Kingdom
$4.13M +$5.24M +479,269 New
WP
35
Woodline Partners
California
$3.65M +$2.7K +247 +0.1%
MAP
36
Moody Aldrich Partners
Massachusetts
$3.55M +$452K +41,352 +10%
NM
37
Newtyn Management
New York
$3.23M -$273K -25,000 -6%
TC
38
TwinBeech Capital
New York
$3.2M +$4.33M +396,048 New
Walleye Capital
39
Walleye Capital
New York
$3.16M -$1.49M -135,858 -26%
Qube Research & Technologies (QRT)
40
Qube Research & Technologies (QRT)
United Kingdom
$3.03M +$3.77M +344,567 +1,137%
Universal-Beteiligungs- und Servicegesellschaft
41
Universal-Beteiligungs- und Servicegesellschaft
Germany
$2.93M +$2.92K +267 +0.1%
BBA
42
Baker Bros. Advisors
New York
$2.78M
PIM
43
Platinum Investment Management
Australia
$2.52M
Principal Financial Group
44
Principal Financial Group
Iowa
$2.49M +$650K +59,399 +24%
Wellington Management Group
45
Wellington Management Group
Massachusetts
$2.42M -$127K -11,634 -4%
Macquarie Group
46
Macquarie Group
Australia
$2.2M +$423K +38,645 +17%
Barclays
47
Barclays
United Kingdom
$2.11M +$718K +65,661 +34%
Bank of New York Mellon
48
Bank of New York Mellon
New York
$2M +$24.9K +2,278 +0.9%
Two Sigma Investments
49
Two Sigma Investments
New York
$1.95M -$1.64M -149,906 -38%
FMI
50
F/M Investments
District of Columbia
$1.94M +$157K +14,384 +6%

WVE Hedge Fund Activity: Q1 2025 in Review

196 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q1 2025, worth a combined $1.06B — down 33% from $1.59B a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new WVE positions and 20 closed out — a net gain of 13 holders — while 83 added to existing stakes and 52 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $31.7M. The largest seller was Millennium Management, cutting an estimated $12.6M.

  • 196 institutional investors held Wave Life Sciences (WVE) as of Q1 2025, up from 183 in Q4 2024.
  • Funds reported $1.06B of Wave Life Sciences stock for Q1 2025, down 33% quarter-over-quarter.
  • 33 funds opened new Wave Life Sciences positions in Q1 2025 and 20 closed out, a net change of +13 holders.
  • The largest Wave Life Sciences buyer in Q1 2025 was Adage Capital Partners, an estimated $31.7M added.
  • The largest Wave Life Sciences seller in Q1 2025 was Millennium Management, an estimated $12.6M sold.

Based on aggregated 13F filings for Q1 2025.