|
1
|
Avoro Capital Advisors
New York
|
$163M
|
+$13M
|
+2,188,888
|
+10%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$160M
|
–
|
–
|
–
|
|
|
3
|
|
$155M
|
+$2.03M
|
+343,473
|
+2%
|
|
|
4
|
|
$141M
|
+$13.8M
|
+2,326,319
|
+13%
|
|
|
5
|
Vestal Point Capital
New York
|
$132M
|
+$8.37M
|
+1,415,000
|
+8%
|
|
|
6
|
|
$112M
|
-$8.75M
|
-1,477,892
|
-8%
|
|
|
7
|
|
$92.3M
|
-$710K
|
-119,990
|
-0.9%
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$90.8M
|
-$5.83M
|
-984,842
|
-7%
|
|
|
9
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$85M
|
+$13.3M
|
+2,247,093
|
+22%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$77.8M
|
+$1.26M
|
+212,842
|
+2%
|
|
|
11
|
Siren LLC
Greenwich,
Connecticut
|
$67.1M
|
+$6.02M
|
+1,016,666
|
+12%
|
|
|
12
|
Octagon Capital Advisors
New York
|
$66M
|
+$4.93M
|
+833,333
|
+9%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$44.7M
|
+$6.09M
|
+1,028,439
|
+19%
|
|
|
14
|
Polar Capital Holdings
London,
United Kingdom
|
$34.8M
|
-$3.18M
|
-537,207
|
-10%
|
|
|
15
|
MPM BioImpact
Boston,
Massachusetts
|
$30.6M
|
+$26.6M
|
+4,500,000
|
New
|
|
|
16
|
|
$30M
|
-$170K
|
-28,649
|
-0.6%
|
|
|
17
|
Baker Bros. Advisors
New York
|
$27.3M
|
–
|
–
|
–
|
|
|
18
|
Wellington Management Group
Boston,
Massachusetts
|
$27.1M
|
+$19.8M
|
+3,349,244
|
+535%
|
|
|
19
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$26.5M
|
+$5.93M
|
+1,002,200
|
+35%
|
|
|
20
|
GordonMD Global Investments
Beverely Hills,
California
|
$24.5M
|
-$85K
|
-14,365
|
-2%
|
|
|
21
|
|
$22.1M
|
–
|
–
|
–
|
|
|
22
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$21.4M
|
+$6.61M
|
+1,117,511
|
+55%
|
|
|
23
|
ADAR1 Capital Management
Austin,
Texas
|
$20.7M
|
+$361K
|
+61,037
|
+2%
|
|
|
24
|
Pictet Asset Management
Carouge,
Switzerland
|
$18.9M
|
+$16.3M
|
+2,751,383
|
+14,243%
|
|
|
25
|
Aberdeen Group
Edinburgh,
United Kingdom
|
$15.8M
|
+$7.73M
|
+1,306,089
|
+128%
|
|
