|
1
|
|
$57.8M
|
+$13.5M
|
+6,233,718
|
+33%
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$54.4M
|
+$27.6M
|
+12,683,145
|
+117%
|
|
|
3
|
Avoro Capital Advisors
New York
|
$50.1M
|
+$3.69M
|
+1,700,001
|
+9%
|
|
|
4
|
|
$39M
|
+$40.6K
|
+18,708
|
+0.1%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$36.1M
|
-$8.98K
|
-4,132
|
-0%
|
|
|
6
|
|
$30.7M
|
-$620K
|
-285,403
|
-2%
|
|
|
7
|
Octagon Capital Advisors
New York
|
$29.1M
|
+$4.11M
|
+1,892,500
|
+18%
|
|
|
8
|
|
$29.1M
|
+$26.6M
|
+12,228,693
|
+3,406%
|
|
|
9
|
Siren LLC
Greenwich,
Connecticut
|
$25.4M
|
+$9.78M
|
+4,500,000
|
+69%
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$25.2M
|
+$4.61M
|
+2,123,206
|
+24%
|
|
|
11
|
Jefferies Financial Group
New York
|
$23.8M
|
+$21.9M
|
+10,068,479
|
+4,105%
|
|
|
12
|
Point72 Asset Management
Stamford,
Connecticut
|
$16.9M
|
+$5.97M
|
+2,747,936
|
+60%
|
|
|
13
|
Deerfield Management
New York
|
$12.4M
|
+$11.7M
|
+5,386,000
|
New
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$11.9M
|
+$4.14M
|
+1,904,798
|
+59%
|
|
|
15
|
Polar Capital Holdings
London,
United Kingdom
|
$11.6M
|
+$4.35M
|
+2,000,000
|
+67%
|
|
|
16
|
Adage Capital Partners
Boston,
Massachusetts
|
$11.2M
|
+$10.5M
|
+4,839,000
|
New
|
|
|
17
|
Toronto Dominion Bank
Toronto, Ontario,
Ontario, Canada
|
$10.9M
|
+$10.3M
|
+4,728,806
|
New
|
|
|
18
|
Tybourne Capital Management
Hong Kong
|
$9.46M
|
+$858K
|
+395,000
|
+11%
|
|
|
19
|
Baker Bros. Advisors
New York
|
$9.25M
|
–
|
–
|
–
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$8.77M
|
+$280K
|
+128,840
|
+4%
|
|
|
21
|
Suvretta Capital Management
New York
|
$7.43M
|
+$6.99M
|
+3,217,449
|
New
|
|
|
22
|
ADAR1 Capital Management
Austin,
Texas
|
$6.95M
|
+$4.22M
|
+1,943,561
|
+182%
|
|
|
23
|
Vestal Point Capital
New York
|
$6.93M
|
+$6.52M
|
+3,000,000
|
New
|
|
|
24
|
MPM BioImpact
Boston,
Massachusetts
|
$6.82M
|
+$6.42M
|
+2,953,562
|
New
|
|
|
25
|
Millennium Management
New York
|
$6.78M
|
+$2.53M
|
+1,163,074
|
+66%
|
|
