|
1
|
RA Capital Management
Boston,
Massachusetts
|
$105M
|
–
|
–
|
–
|
|
|
2
|
|
$100M
|
+$40.3M
|
+8,676,906
|
+63%
|
|
|
3
|
Avoro Capital Advisors
New York
|
$97M
|
–
|
–
|
–
|
|
|
4
|
|
$82.1M
|
-$1.29M
|
-277,521
|
-1%
|
|
|
5
|
Vestal Point Capital
New York
|
$80.5M
|
+$19.8M
|
+4,250,000
|
+31%
|
|
|
6
|
|
$80.3M
|
-$526K
|
-113,147
|
-0.6%
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$64M
|
+$3.69M
|
+792,889
|
+6%
|
|
|
8
|
|
$61.2M
|
-$12.6M
|
-2,718,049
|
-17%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$50.1M
|
+$1.95M
|
+418,994
|
+4%
|
|
|
10
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$45.7M
|
+$47.6M
|
+10,231,502
|
New
|
|
|
11
|
Octagon Capital Advisors
New York
|
$39.6M
|
–
|
–
|
–
|
|
|
12
|
Siren LLC
Greenwich,
Connecticut
|
$39.5M
|
-$6.04M
|
-1,300,000
|
-13%
|
|
|
13
|
Polar Capital Holdings
London,
United Kingdom
|
$25.3M
|
-$10.6M
|
-2,277,063
|
-29%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$24.7M
|
+$674K
|
+144,929
|
+3%
|
|
|
15
|
GordonMD Global Investments
Beverely Hills,
California
|
$22.2M
|
-$2.76M
|
-593,351
|
-45%
|
|
|
16
|
|
$19.8M
|
+$1.92M
|
+413,666
|
+10%
|
|
|
17
|
Baker Bros. Advisors
New York
|
$17.9M
|
–
|
–
|
–
|
|
|
18
|
Millennium Management
New York
|
$14.7M
|
+$479K
|
+102,957
|
+3%
|
|
|
19
|
|
$14.5M
|
+$8.14M
|
+1,750,000
|
+117%
|
|
|
20
|
ADAR1 Capital Management
Austin,
Texas
|
$13.3M
|
+$2.25M
|
+483,620
|
+19%
|
|
|
21
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$12.9M
|
-$3.9M
|
-838,699
|
-23%
|
|
|
22
|
Deerfield Management
New York
|
$12.2M
|
–
|
–
|
–
|
|
|
23
|
Barclays
London,
United Kingdom
|
$11.4M
|
-$12.7M
|
-2,726,991
|
-49%
|
|
|
24
|
SG Americas Securities
New York
|
$9.73M
|
+$6.49M
|
+1,395,268
|
+179%
|
|
|
25
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$9.04M
|
+$9.4M
|
+2,022,498
|
New
|
|
