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SLRN

ACELYRIN

Delisted

SLRN was delisted on the 21st of May, 2025.

109 hedge funds and large institutions have $613M invested in ACELYRIN in 2024 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 46 increasing their positions, 27 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

70% more repeat investments, than reductions

Existing positions increased: 46 | Existing positions reduced: 27

5.32% more ownership

Funds ownership: 88.02%93.35% (+5.3%)

1% less funds holding

Funds holding: 110109 (-1)

4% less first-time investments, than exits

New positions opened: 25 | Existing positions closed: 26

4% less capital invested

Capital invested by funds: $639M → $613M (-$25.9M)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

29% less call options, than puts

Call options by funds: $4.79M | Put options by funds: $6.78M

Holders
109
Holders Change
-1
Holders Change %
-0.91%
% of All Funds
1.57%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.07%
New
25
Increased
46
Reduced
27
Closed
26
Calls
$4.79M
Puts
$6.78M
Net Calls
-$1.99M
Net Calls Change
-$6.43M
Name Holding Trade Value Shares
Change
Change in
Stake
ACMC
1
AyurMaya Capital Management Company
New Hampshire
$63M
Fidelity Investments
2
Fidelity Investments
Massachusetts
$47.8M -$13.2M -1,743,061 -20%
Citadel Advisors
3
Citadel Advisors
Florida
$47.4M +$4.21M +554,789 +9%
Vanguard Group
4
Vanguard Group
Pennsylvania
$42.1M +$620K +81,633 +1%
BlackRock
5
BlackRock
New York
$32.4M +$14.3M +1,885,172 +65%
Millennium Management
6
Millennium Management
New York
$27.1M +$30.5M +4,013,528 New
O
7
OrbiMed
New York
$27M
VP
8
venBio Partners
California
$26M
Adage Capital Partners
9
Adage Capital Partners
Massachusetts
$22.1M +$23.5M +3,100,000 +1,722%
TCM
10
Tybourne Capital Management
Hong Kong
$19.6M
GA
11
General Atlantic
New York
$19.5M
BOCH
12
Blue Owl Capital Holdings
New York
$19.1M +$4.05M +533,038 +23%
JP Morgan Chase
13
JP Morgan Chase
New York
$17.5M -$4.53M -596,673 -19%
SB
14
Samsara BioCapital
California
$17M
AG
15
Artal Group
Luxembourg
$16.2M -$4.79M -630,745 -21%
T. Rowe Price Investment Management
16
T. Rowe Price Investment Management
Maryland
$14.3M +$16.1M +2,119,591 New
Franklin Resources
17
Franklin Resources
California
$13.8M +$9.41M +1,238,453 +154%
PAI
18
Palo Alto Investors
California
$11.6M +$13M +1,715,180 New
OM
19
Opaleye Management
Massachusetts
$10.7M -$19.5M -2,566,138 -62%
IC
20
Ikarian Capital
Texas
$10.6M -$3.24M -426,665 -21%
Geode Capital Management
21
Geode Capital Management
Massachusetts
$8.3M +$3.46M +455,864 +59%
State Street
22
State Street
Massachusetts
$7.62M +$3.52M +463,382 +70%
WP
23
Woodline Partners
California
$6.89M +$552K +72,645 +8%
RI
24
RTW Investments
New York
$6.6M
VA
25
VR Adviser
New York
$6.33M

SLRN Hedge Fund Activity: Q1 2024 in Review

109 of the 6,942 institutional investors tracked by Wall St. Rank reported a position in ACELYRIN (SLRN) for Q1 2024, worth a combined $613M — down 4.1% from $639M a quarter earlier.

Sellers outnumbered buyers: 26 funds closed out of SLRN and 25 opened new positions — a net loss of 1 holder — while 27 trimmed existing stakes and 46 added.

The largest buyer was Millennium Management, opening a new position worth an estimated $30.5M. The largest seller was Opaleye Management, cutting an estimated $19.5M.

  • 109 institutional investors held ACELYRIN (SLRN) as of Q1 2024, down from 110 in Q4 2023.
  • Funds reported $613M of ACELYRIN stock for Q1 2024, down 4.1% quarter-over-quarter.
  • 25 funds opened new ACELYRIN positions in Q1 2024 and 26 closed out, a net change of -1 holder.
  • The largest ACELYRIN buyer in Q1 2024 was Millennium Management, an estimated $30.5M added.
  • The largest ACELYRIN seller in Q1 2024 was Opaleye Management, an estimated $19.5M sold.

Based on aggregated 13F filings for Q1 2024.