Opaleye Management’s ACELYRIN SLRN Stock Holding History

Opaleye Management’s Portfolio SLRN Stock Details SLRN Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q2	–	Sell	-1,615,000	Closed	-$3.99M	–	48
2025 Q1	$3.99M	Sell	1,615,000 -620,000	-28%	-$1.47M	0.89%	26
2024 Q4	$7.17M	Buy	2,235,000 +341,340	+18%	+$1.65M	1.26%	17
2024 Q3	$9.34M	Buy	1,893,660 +313,660	+20%	+$1.62M	1.56%	16
2024 Q2	$6.97M	Hold	1,580,000	–	–	1.59%	20
2024 Q1	$10.7M	Sell	1,580,000 -2,566,138	-62%	-$19.5M	2.32%	15
2023 Q4	$30.9M	Hold	4,146,138	–	–	8.22%	3
2023 Q3	$42.2M	Sell	4,146,138 -12,500	-0.3%	-$265K	13.72%	2
2023 Q2	$86.9M	Buy	+4,158,638	New	+$85.1M	20.79%	1

Other funds holding SLRN

Osaic Holdings Scottsdale, Arizona $68.3B AUM 20.5% 1-Year Est. Return

IFP Advisors Tampa, Florida $5.54B AUM 27.43% 1-Year Est. Return

Opaleye Management's SLRN Position: Q2 2025 in Review

Opaleye Management sold out of ACELYRIN (SLRN) in Q2 2025, closing a stake of 1,615,000 shares — an estimated $3.99M sold.

Opaleye Management first reported a position in SLRN in Q2 2023 and held it in 8 quarters. The position peaked at $86.9M in Q2 2023. 2 funds tracked by Wall St. Rank hold SLRN as of Q2 2025.

Opaleye Management reported no remaining ACELYRIN position as of Q2 2025 after selling out during the quarter.
Opaleye Management sold 1,615,000 ACELYRIN shares in Q2 2025, an estimated $3.99M.
Opaleye Management first reported a position in ACELYRIN in Q2 2023 and held it in 8 quarters.
Opaleye Management's ACELYRIN position peaked at $86.9M in Q2 2023.
2 funds tracked by Wall St. Rank held ACELYRIN as of Q2 2025.

Based on Opaleye Management's 13F filing for Q2 2025, filed 14 Aug 2025.