SLRN

ACELYRIN
SLRN

Overview Fund Activity
Delisted

SLRN was delisted on the 21st of May, 2025.

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110 hedge funds and large institutions have $639M invested in ACELYRIN in 2023 Q4 according to their latest regulatory filings, with 35 funds opening new positions, 31 increasing their positions, 28 reducing their positions, and 24 closing their positions.

Holders
110
Holders Change
+9
Holders Change %
+8.91%
% of All Funds
1.61%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.09%
New
35
Increased
31
Reduced
28
Closed
24
Calls
$4.96M
Puts
$513K
Net Calls
+$4.45M
Net Calls Change
+$6.94M

Top Buyers

1
Vanguard Group
1
Vanguard Group
Pennsylvania
$45.9M
2
BOCH
2
Blue Owl Capital Holdings
New York
$17.1M
3
Morgan Stanley
3
Morgan Stanley
New York
$13.2M
4
LGM
4
Logos Global Management
California
$9.33M
5
BlackRock
5
BlackRock
New York
$21.7M

Top Sellers

1
EC
1
EcoR1 Capital
California
$0
2
DCM
2
Driehaus Capital Management
Illinois
$0
3
O
3
OrbiMed
New York
$29.9M
4
State Street
4
State Street
Massachusetts
$4.96M
5
IC
5
Ikarian Capital
Texas
$14.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
ACMC
1
AyurMaya Capital Management Company
New Hampshire
$69.6M – – –
Fidelity Investments
2
Fidelity Investments
Massachusetts
$65.8M -$1.04M -139,455 -2%
Citadel Advisors
3
Citadel Advisors
Florida
$48.3M +$4.08M +547,355 +9%
Vanguard Group
4
Vanguard Group
Pennsylvania
$45.9M +$22.1M +2,966,883 +93%
OM
5
Opaleye Management
Massachusetts
$30.9M – – –
O
6
OrbiMed
New York
$29.9M -$9.88M -1,324,591 -25%
VP
7
venBio Partners
California
$28.7M – – –
JPMorgan Chase & Co
8
JPMorgan Chase & Co
New York
$23.8M +$182K +24,386 +0.8%
AG
9
Artal Group
Luxembourg
$22.6M +$4.23M +566,609 +23%
BlackRock
10
BlackRock
New York
$21.7M +$5.29M +709,436 +32%
TCM
11
Tybourne Capital Management
Hong Kong
$21.7M +$5.04M +676,187 +30%
GA
12
General Atlantic
New York
$21.6M – – –
SB
13
Samsara BioCapital
California
$18.8M +$1.06M +141,443 +6%
BOCH
14
Blue Owl Capital Holdings
New York
$17.1M +$17.1M +2,292,990 New
IC
15
Ikarian Capital
Texas
$14.9M -$6.92M -927,421 -32%
Morgan Stanley
16
Morgan Stanley
New York
$13.2M +$11.3M +1,513,865 +607%
Janus Henderson Group
17
Janus Henderson Group
United Kingdom
$12M -$1.44M -192,537 -11%
DC
18
Decheng Capital
California
$10.2M +$10.2M +1,370,951 New
LGM
19
Logos Global Management
California
$9.33M +$9.33M +1,250,000 New
KCM
20
Kynam Capital Management
New Jersey
$8.95M – – –
Goldman Sachs
21
Goldman Sachs
New York
$8.35M -$4.93M -660,914 -37%
RI
22
RTW Investments
New York
$7.3M – – –
WP
23
Woodline Partners
California
$7.08M +$303K +40,646 +4%
VA
24
VR Adviser
New York
$6.99M +$543K +72,781 +8%
Marshall Wace
25
Marshall Wace
United Kingdom
$6.67M – – –
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