SLRN

ACELYRIN
SLRN

Overview Fund Activity
Delisted

SLRN was delisted on the 21st of May, 2025.

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101 hedge funds and large institutions have $847M invested in ACELYRIN in 2023 Q3 according to their latest regulatory filings, with 47 funds opening new positions, 20 increasing their positions, 23 reducing their positions, and 28 closing their positions.

Holders
101
Holders Change
+19
Holders Change %
+23.17%
% of All Funds
1.61%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.11%
New
47
Increased
20
Reduced
23
Closed
28
Calls
$3.2M
Puts
$5.7M
Net Calls
-$2.5M
Net Calls Change
-$5.21M

Top Buyers

1
State Street
1
State Street
Massachusetts
$20.1M
2
Janus Henderson Group
2
Janus Henderson Group
United Kingdom
$16.4M
3
Fidelity Investments
3
Fidelity Investments
Massachusetts
$89.9M
4
Goldman Sachs
4
Goldman Sachs
New York
$18.1M
5
EC
5
EcoR1 Capital
California
$14.3M

Top Sellers

1
Wellington Management Group
1
Wellington Management Group
Massachusetts
$0
2
APM
2
Avidity Partners Management
Texas
$0
3
Millennium Management
3
Millennium Management
New York
$0
4
DM
4
Deerfield Management
New York
$0
5
AllianceBernstein
5
AllianceBernstein
Tennessee
$254K
Name Market Value Shares Shares
Change 		Shares
Change %
ACMC
1
AyurMaya Capital Management Company
New Hampshire
$94.9M 9,334,735 – –
Fidelity Investments
2
Fidelity Investments
Massachusetts
$89.9M 8,961,726 +1,505,488 +20%
Citadel Advisors
3
Citadel Advisors
Florida
$57.9M 5,926,693 -112,964 -2%
O
4
OrbiMed
New York
$54.2M 5,326,302 – –
OM
5
Opaleye Management
Massachusetts
$42.2M 4,146,138 -12,500 -0.3%
VP
6
venBio Partners
California
$39.2M 3,852,470 -4,760 -0.1%
Vanguard Group
7
Vanguard Group
Pennsylvania
$32.4M 3,189,027 +116,847 +4%
JPMorgan Chase & Co
8
JPMorgan Chase & Co
New York
$32.2M 3,164,091 -539,247 -15%
IC
9
Ikarian Capital
Texas
$29.7M 2,918,426 – –
GA
10
General Atlantic
New York
$29.4M 2,889,668 +1,389,668 +93%
AG
11
Artal Group
Luxembourg
$25.1M 2,469,279 +648,065 +36%
SB
12
Samsara BioCapital
California
$24.2M 2,381,579 +125,557 +6%
CA
13
CHI Advisors
New York
$23M 2,262,990 -400,816 -15%
TCM
14
Tybourne Capital Management
Hong Kong
$22.7M 2,230,442 – –
BlackRock
15
BlackRock
New York
$22.4M 2,198,122 +1,350,227 +159%
State Street
16
State Street
Massachusetts
$20.1M 1,980,316 +1,863,316 +1,593%
Goldman Sachs
17
Goldman Sachs
New York
$18.1M 1,779,825 +1,469,827 +474%
Janus Henderson Group
18
Janus Henderson Group
United Kingdom
$16.4M 1,794,692 +1,794,692 New
DCMIC
19
Decheng Capital Management III (Cayman)
Cayman Islands
$15.7M 1,548,317 -6,100 -0.4%
EC
20
EcoR1 Capital
California
$14.3M 1,402,201 +1,402,201 New
DCM
21
Driehaus Capital Management
Illinois
$13.4M 1,319,349 -439,448 -25%
KCM
22
Kynam Capital Management
New Jersey
$12.2M 1,200,000 +1,200,000 New
RI
23
RTW Investments
New York
$9.95M 978,310 – –
WP
24
Woodline Partners
California
$9.23M 907,913 -127,642 -12%
Marshall Wace
25
Marshall Wace
United Kingdom
$9.09M 894,182 -267,346 -23%
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