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SLRN

ACELYRIN
SLRN

Delisted

SLRN was delisted on the 21st of May, 2025.

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2 hedge funds and large institutions have $704 invested in ACELYRIN in 2025 Q2 according to their latest regulatory filings, with 2 funds opening new positions, 0 increasing their positions, 0 reducing their positions, and 105 closing their positions.

New
Increased
Maintained
Reduced
Closed

73.41% less ownership

Funds ownership: 73.41% → 0% (-73%)

98% less funds holding

Funds holding: 105 → 2 (-103)

98% less first-time investments, than exits

New positions opened: 2 | Existing positions closed: 105

100% less funds holding in top 10

Funds holding in top 10: 4 → 0 (-4)

100% less capital invested

Capital invested by funds: $183M → $704 (-$183M)

Holders
2
Holders Change
-103
Holders Change %
-98.1%
% of All Funds
0.03%
Holding in Top 10
–
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-100%
% of All Funds
–
New
2
Increased
–
Reduced
–
Closed
105
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
Osaic Holdings
Osaic Holdings
Arizona
+$654
2
IA
IFP Advisors
Florida
+$7

Top Sellers

Rank Fund Capital Flow
1
TCM
Tang Capital Management
California
-$24.3M
2
ACMC
AyurMaya Capital Management Company
New Hampshire
-$23.1M
3
BlackRock
BlackRock
New York
-$14.3M
4
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
-$11.5M
5
MAP
Madison Avenue Partners
New York
-$10.2M
Name Holding Trade Value Shares
Change 		Change in
Stake
Osaic Holdings
1
Osaic Holdings
Arizona
$697 +$654 +282 New
IA
2
IFP Advisors
Florida
$7 +$7 +3 New
TCM
3
Tang Capital Management
California
– -$24.3M -9,818,115 Closed
ACMC
4
AyurMaya Capital Management Company
New Hampshire
– -$23.1M -9,334,735 Closed
BlackRock
5
BlackRock
New York
– -$14.3M -5,805,096 Closed
T. Rowe Price Investment Management
6
T. Rowe Price Investment Management
Maryland
– -$11.5M -4,649,865 Closed
MAP
7
Madison Avenue Partners
New York
– -$10.2M -4,142,640 Closed
Vanguard Group
8
Vanguard Group
Pennsylvania
– -$10.1M -4,079,706 Closed
O
9
OrbiMed
New York
– -$9.88M -4,001,711 Closed
VP
10
venBio Partners
California
– -$9.4M -3,806,410 Closed
VCIM
11
Velan Capital Investment Management
Georgia
– -$8.32M -3,366,945 Closed
TCM
12
Tybourne Capital Management
Hong Kong
– -$7.18M -2,906,629 Closed
GA
13
General Atlantic
New York
– -$6.66M -2,695,327 Closed
SB
14
Samsara BioCapital
California
– -$6.23M -2,523,022 Closed
PAI
15
Palo Alto Investors
California
– -$4.43M -1,792,895 Closed
Geode Capital Management
16
Geode Capital Management
Massachusetts
– -$4.38M -1,773,818 Closed
OM
17
Opaleye Management
Massachusetts
– -$3.99M -1,615,000 Closed
State Street
18
State Street
Massachusetts
– -$3.51M -1,420,068 Closed
Balyasny Asset Management
19
Balyasny Asset Management
Illinois
– -$3.22M -1,305,015 Closed
Alyeska Investment Group
20
Alyeska Investment Group
Illinois
– -$1.52M -615,878 Closed
Renaissance Technologies
21
Renaissance Technologies
New York
– -$1.48M -599,800 Closed
Northern Trust
22
Northern Trust
Illinois
– -$1.48M -598,151 Closed
JP Morgan Chase
23
JP Morgan Chase
New York
– -$1.46M -590,846 Closed
CF
24
Cantor Fitzgerald
New York
– -$1.45M -588,664 Closed
Charles Schwab
25
Charles Schwab
California
– -$1.35M -544,575 Closed
1
2 3 4 5

SLRN Hedge Fund Activity: Q2 2025 in Review

2 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in ACELYRIN (SLRN) for Q2 2025, worth a combined $704 — down 100% from $183M a quarter earlier.

Sellers outnumbered buyers: 105 funds closed out of SLRN and 2 opened new positions — a net loss of 103 holders — while 0 trimmed existing stakes and 0 added.

The largest buyer was Osaic Holdings, opening a new position worth an estimated $654. The largest seller was Tang Capital Management, exiting entirely with an estimated $24.3M sold.

  • 2 institutional investors held ACELYRIN (SLRN) as of Q2 2025, down from 105 in Q1 2025.
  • Funds reported $704 of ACELYRIN stock for Q2 2025, down 100% quarter-over-quarter.
  • 2 funds opened new ACELYRIN positions in Q2 2025 and 105 closed out, a net change of -103 holders.
  • The largest ACELYRIN buyer in Q2 2025 was Osaic Holdings, an estimated $654 added.
  • The largest ACELYRIN seller in Q2 2025 was Tang Capital Management, an estimated $24.3M sold.

Based on aggregated 13F filings for Q2 2025.