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SLRN

ACELYRIN

Delisted

SLRN was delisted on the 21st of May, 2025.

125 hedge funds and large institutions have $276M invested in ACELYRIN in 2024 Q4 according to their latest regulatory filings, with 18 funds opening new positions, 44 increasing their positions, 40 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed

450% more call options, than puts

Call options by funds: $22K | Put options by funds: $4K

29% more first-time investments, than exits

New positions opened: 18 | Existing positions closed: 14

10% more repeat investments, than reductions

Existing positions increased: 44 | Existing positions reduced: 40

2% more funds holding

Funds holding: 122125 (+3)

0.28% more ownership

Funds ownership: 87.41%87.69% (+0.28%)

33% less funds holding in top 10

Funds holding in top 10: 32 (-1)

36% less capital invested

Capital invested by funds: $430M → $276M (-$154M)

Holders
125
Holders Change
+3
Holders Change %
+2.46%
% of All Funds
1.65%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
18
Increased
44
Reduced
40
Closed
14
Calls
$22K
Puts
$4K
Net Calls
+$18K
Net Calls Change
+$136K
Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Investment Management
1
T. Rowe Price Investment Management
Maryland
$40.4M +$11.8M +2,440,278 +23%
ACMC
2
AyurMaya Capital Management Company
New Hampshire
$29.3M
BlackRock
3
BlackRock
New York
$18.9M +$186K +38,494 +0.6%
Millennium Management
4
Millennium Management
New York
$14.8M -$3.74M -772,770 -14%
Citadel Advisors
5
Citadel Advisors
Florida
$13.2M -$11.2M -2,311,390 -35%
Vanguard Group
6
Vanguard Group
Pennsylvania
$12.8M +$63K +13,021 +0.3%
O
7
OrbiMed
New York
$12.6M
VP
8
venBio Partners
California
$12M -$223K -46,060 -1%
TCM
9
Tybourne Capital Management
Hong Kong
$9.13M
BOCH
10
Blue Owl Capital Holdings
New York
$8.74M -$48.4K -10,000 -0.4%
GA
11
General Atlantic
New York
$8.46M -$941K -194,341 -7%
SB
12
Samsara BioCapital
California
$7.92M
Morgan Stanley
13
Morgan Stanley
New York
$7.3M +$2.6M +537,068 +30%
OM
14
Opaleye Management
Massachusetts
$7.17M +$1.65M +341,340 +18%
PAI
15
Palo Alto Investors
California
$5.63M
SL
16
Siren LLC
Connecticut
$5.43M
Geode Capital Management
17
Geode Capital Management
Massachusetts
$5.37M +$278K +57,472 +3%
SC
18
Stempoint Capital
New York
$5.35M +$1.87M +386,971 +29%
Alyeska Investment Group
19
Alyeska Investment Group
Illinois
$4.76M +$7.34M +1,515,878 New
State Street
20
State Street
Massachusetts
$4.53M +$814K +168,177 +13%
RI
21
RTW Investments
New York
$3.07M
KCM
22
Kynam Capital Management
New Jersey
$2.66M
IC
23
Ikarian Capital
Texas
$2.12M -$2.26K -466 -0.1%
Jacobs Levy Equity Management
24
Jacobs Levy Equity Management
New Jersey
$2.08M -$3.21M -663,410 -50%
Northern Trust
25
Northern Trust
Illinois
$1.98M +$112K +23,130 +4%

SLRN Hedge Fund Activity: Q4 2024 in Review

125 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in ACELYRIN (SLRN) for Q4 2024, worth a combined $276M — down 36% from $430M a quarter earlier.

Buyers outnumbered sellers: 18 funds opened new SLRN positions and 14 closed out — a net gain of 4 holders — while 44 added to existing stakes and 40 trimmed.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $11.8M. The largest seller was Citadel Advisors, cutting an estimated $11.2M.

  • 125 institutional investors held ACELYRIN (SLRN) as of Q4 2024, up from 122 in Q3 2024.
  • Funds reported $276M of ACELYRIN stock for Q4 2024, down 36% quarter-over-quarter.
  • 18 funds opened new ACELYRIN positions in Q4 2024 and 14 closed out, a net change of +4 holders.
  • The largest ACELYRIN buyer in Q4 2024 was T. Rowe Price Investment Management, an estimated $11.8M added.
  • The largest ACELYRIN seller in Q4 2024 was Citadel Advisors, an estimated $11.2M sold.

Based on aggregated 13F filings for Q4 2024.