|
1
|
SB Investment Advisers (UK)
London,
United Kingdom
|
$350M
|
–
|
–
|
–
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$132M
|
+$361K
|
+29,053
|
+0.3%
|
|
|
3
|
|
$105M
|
+$5.37M
|
+432,038
|
+5%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$105M
|
+$18.4M
|
+1,482,557
|
+22%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$90.6M
|
+$16.5M
|
+1,330,516
|
+23%
|
|
|
6
|
|
$75.3M
|
+$3.73M
|
+300,000
|
+5%
|
|
|
7
|
|
$62.7M
|
+$8.63M
|
+694,079
|
+16%
|
|
|
8
|
Bellevue Group
Kuesnacht,
Switzerland
|
$52.4M
|
-$22.4K
|
-1,800
|
-0%
|
|
|
9
|
EcoR1 Capital
San Francisco,
California
|
$52.3M
|
–
|
–
|
–
|
|
|
10
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$42.9M
|
+$9.31M
|
+748,472
|
+28%
|
|
|
11
|
BVF Inc
San Francisco,
California
|
$39.2M
|
–
|
–
|
–
|
|
|
12
|
Fidelity Investments
Boston,
Massachusetts
|
$37.1M
|
-$72.8M
|
-5,850,770
|
-66%
|
|
|
13
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$28.4M
|
+$520K
|
+41,780
|
+2%
|
|
|
14
|
Perceptive Advisors
New York
|
$24.4M
|
–
|
–
|
–
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$23.6M
|
+$1.58M
|
+126,730
|
+7%
|
|
|
16
|
AllianceBernstein
Nashville,
Tennessee
|
$23.5M
|
+$4.79M
|
+385,116
|
+26%
|
|
|
17
|
Boxer Capital
San Diego,
California
|
$22.8M
|
-$4.35M
|
-350,000
|
-16%
|
|
|
18
|
|
$20.3M
|
–
|
–
|
–
|
|
|
19
|
Millennium Management
New York
|
$19.8M
|
+$19.6M
|
+1,574,157
|
New
|
|
|
20
|
Alphabet Inc
Mountain View,
California
|
$19.7M
|
–
|
–
|
–
|
|
|
21
|
MPM BioImpact
Boston,
Massachusetts
|
$17M
|
+$1.6M
|
+128,734
|
+11%
|
|
|
22
|
|
$16.2M
|
-$1.36M
|
-109,648
|
-8%
|
|
|
23
|
|
$15.2M
|
-$5.72M
|
-460,018
|
-27%
|
|
|
24
|
Dimensional Fund Advisors
Austin,
Texas
|
$14.6M
|
-$888K
|
-71,409
|
-6%
|
|
|
25
|
|
$14.6M
|
–
|
–
|
–
|
|
