|
1
|
SB Investment Advisers (UK)
London,
United Kingdom
|
$624M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$268M
|
-$30.2M
|
-1,376,843
|
-10%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$187M
|
+$27.7M
|
+1,261,066
|
+18%
|
|
|
4
|
|
$151M
|
+$3.96M
|
+180,459
|
+3%
|
|
|
5
|
|
$112M
|
+$1.67M
|
+76,225
|
+2%
|
|
|
6
|
|
$105M
|
+$13.5M
|
+614,858
|
+15%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$102M
|
-$16.2M
|
-738,944
|
-14%
|
|
|
8
|
BVF Inc
San Francisco,
California
|
$97.1M
|
-$994K
|
-45,284
|
-1%
|
|
|
9
|
Bellevue Group
Kuesnacht,
Switzerland
|
$94.1M
|
+$3.79M
|
+172,558
|
+4%
|
|
|
10
|
EcoR1 Capital
San Francisco,
California
|
$93.1M
|
+$9.66M
|
+440,283
|
+12%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$82.1M
|
-$24.4M
|
-1,110,349
|
-23%
|
|
|
12
|
Driehaus Capital Management
Chicago,
Illinois
|
$66.4M
|
-$2.75M
|
-125,281
|
-4%
|
|
|
13
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$56.2M
|
-$7.2M
|
-328,205
|
-12%
|
|
|
14
|
Boxer Capital
San Diego,
California
|
$48.5M
|
-$11M
|
-500,000
|
-19%
|
|
|
15
|
Perceptive Advisors
New York
|
$43.5M
|
–
|
–
|
–
|
|
|
16
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$40.5M
|
+$39.8M
|
+1,811,603
|
New
|
|
|
17
|
|
$38.7M
|
+$6.88M
|
+313,499
|
+22%
|
|
|
18
|
Alphabet Inc
Mountain View,
California
|
$35.1M
|
–
|
–
|
–
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$34.7M
|
+$2.73M
|
+124,251
|
+9%
|
|
|
20
|
|
$32.5M
|
+$16.6M
|
+754,716
|
+108%
|
|
|
21
|
|
$31.9M
|
+$10.2M
|
+466,520
|
+49%
|
|
|
22
|
AllianceBernstein
Nashville,
Tennessee
|
$31.4M
|
-$10.3M
|
-469,839
|
-25%
|
|
|
23
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$25.9M
|
+$13.2M
|
+601,604
|
+108%
|
|
|
24
|
|
$18.6M
|
+$1.05M
|
+47,917
|
+6%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$18.3M
|
+$414K
|
+18,886
|
+2%
|
|
