|
1
|
SB Investment Advisers (UK)
London,
United Kingdom
|
$965M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$201M
|
+$46.3M
|
+1,066,214
|
+22%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$140M
|
+$101M
|
+2,330,406
|
+135%
|
|
|
4
|
|
$131M
|
+$27.9M
|
+641,756
|
+20%
|
|
|
5
|
EcoR1 Capital
San Francisco,
California
|
$119M
|
+$9.93M
|
+228,714
|
+7%
|
|
|
6
|
|
$117M
|
-$18.8M
|
-433,836
|
-11%
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$99.3M
|
-$8.68M
|
-200,000
|
-7%
|
|
|
8
|
Driehaus Capital Management
Chicago,
Illinois
|
$87.9M
|
+$62.8M
|
+1,446,339
|
+132%
|
|
|
9
|
Foresite Capital Management IV
Larkspur,
California
|
$74M
|
–
|
–
|
–
|
|
|
10
|
Gilder Gagnon Howe & Co
New York
|
$69.8M
|
-$2.02M
|
-46,470
|
-2%
|
|
|
11
|
Perceptive Advisors
New York
|
$69.8M
|
-$13.5M
|
-311,310
|
-13%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$69.7M
|
+$29.9M
|
+688,871
|
+52%
|
|
|
13
|
Bellevue Group
Kuesnacht,
Switzerland
|
$66.8M
|
+$22.7M
|
+521,987
|
+37%
|
|
|
14
|
Alphabet Inc
Mountain View,
California
|
$54.2M
|
-$10.1M
|
-233,004
|
-13%
|
|
|
15
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$52M
|
+$31.7M
|
+731,517
|
+95%
|
|
|
16
|
|
$47.7M
|
+$3.86M
|
+88,977
|
+7%
|
|
|
17
|
Boxer Capital
San Diego,
California
|
$44.7M
|
–
|
–
|
–
|
|
|
18
|
AllianceBernstein
Nashville,
Tennessee
|
$36.4M
|
+$10.1M
|
+232,522
|
+28%
|
|
|
19
|
RA Capital Management
Boston,
Massachusetts
|
$34.6M
|
–
|
–
|
–
|
|
|
20
|
|
$33.4M
|
+$12M
|
+276,986
|
+40%
|
|
|
21
|
Wellington Management Group
Boston,
Massachusetts
|
$29.2M
|
+$30.4M
|
+701,573
|
+489%
|
|
|
22
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$28.3M
|
+$10.9M
|
+250,000
|
+44%
|
|
|
23
|
Darwin Global Management
St. Helier,
Jersey
|
$27.1M
|
+$34M
|
+782,471
|
New
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$20.9M
|
+$6.85M
|
+157,909
|
+35%
|
|
|
25
|
Bessemer Group
Woodbridge,
New Jersey
|
$20.2M
|
+$2.31M
|
+53,339
|
+10%
|
|
