|
1
|
SB Investment Advisers (UK)
London,
United Kingdom
|
$1.16B
|
–
|
–
|
–
|
|
|
2
|
TRV GP III
Boston,
Massachusetts
|
$439M
|
–
|
–
|
–
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$198M
|
-$2.42M
|
-53,641
|
-1%
|
|
|
4
|
|
$158M
|
–
|
–
|
–
|
|
|
5
|
EcoR1 Capital
San Francisco,
California
|
$133M
|
–
|
–
|
–
|
|
|
6
|
|
$131M
|
+$49.3M
|
+1,091,529
|
+53%
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$128M
|
-$13.8M
|
-305,233
|
-9%
|
|
|
8
|
TRV GP IV
Boston,
Massachusetts
|
$117M
|
–
|
–
|
–
|
|
|
9
|
Perceptive Advisors
New York
|
$96.8M
|
–
|
–
|
–
|
|
|
10
|
Foresite Capital Management IV
Larkspur,
California
|
$88.9M
|
–
|
–
|
–
|
|
|
11
|
Gilder Gagnon Howe & Co
New York
|
$85.9M
|
+$1.87M
|
+41,430
|
+2%
|
|
|
12
|
Alphabet Inc
Mountain View,
California
|
$74.9M
|
–
|
–
|
–
|
|
|
13
|
Vanguard Group
Malvern,
Pennsylvania
|
$71.5M
|
+$4.01M
|
+88,701
|
+5%
|
|
|
14
|
Bellevue Group
Kuesnacht,
Switzerland
|
$58.6M
|
+$4.94M
|
+109,357
|
+8%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$55.1M
|
+$38.4M
|
+848,817
|
+178%
|
|
|
16
|
Boxer Capital
San Diego,
California
|
$53.8M
|
+$1.91M
|
+42,173
|
+3%
|
|
|
17
|
|
$53.6M
|
+$3.44M
|
+76,091
|
+6%
|
|
|
18
|
Driehaus Capital Management
Chicago,
Illinois
|
$45.6M
|
+$1.05M
|
+23,271
|
+2%
|
|
|
19
|
RA Capital Management
Boston,
Massachusetts
|
$41.6M
|
–
|
–
|
–
|
|
|
20
|
AllianceBernstein
Nashville,
Tennessee
|
$34.1M
|
+$5.36M
|
+118,608
|
+17%
|
|
|
21
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$32.1M
|
-$630K
|
-13,927
|
-2%
|
|
|
22
|
|
$28.6M
|
+$26.3M
|
+582,855
|
+548%
|
|
|
23
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$23.6M
|
+$3.09M
|
+68,309
|
+14%
|
|
|
24
|
Harvard Management Company
Boston,
Massachusetts
|
$22.5M
|
–
|
–
|
–
|
|
|
25
|
Bessemer Group
Woodbridge,
New Jersey
|
$22.1M
|
–
|
–
|
–
|
|
