|
1
|
SB Investment Advisers (UK)
London,
United Kingdom
|
$835M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$486M
|
+$859K
|
+35,405
|
+0.2%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$186M
|
+$465K
|
+19,181
|
+0.3%
|
|
|
4
|
|
$179M
|
-$471K
|
-19,430
|
-0.3%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$150M
|
+$20.5M
|
+844,377
|
+20%
|
|
|
6
|
BVF Inc
San Francisco,
California
|
$136M
|
+$34M
|
+1,400,000
|
+45%
|
|
|
7
|
Driehaus Capital Management
Chicago,
Illinois
|
$121M
|
+$396K
|
+16,332
|
+0.4%
|
|
|
8
|
Bellevue Group
Kuesnacht,
Switzerland
|
$117M
|
-$4.54M
|
-187,000
|
-5%
|
|
|
9
|
|
$115M
|
–
|
–
|
–
|
|
|
10
|
|
$98M
|
-$2.25M
|
-92,923
|
-3%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$97.4M
|
+$1.63M
|
+67,170
|
+2%
|
|
|
12
|
Boxer Capital
San Diego,
California
|
$79.9M
|
–
|
–
|
–
|
|
|
13
|
EcoR1 Capital
San Francisco,
California
|
$68.6M
|
+$12.4M
|
+512,357
|
+29%
|
|
|
14
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$60.6M
|
-$199K
|
-8,210
|
-0.4%
|
|
|
15
|
Wellington Management Group
Boston,
Massachusetts
|
$60.5M
|
+$533K
|
+21,966
|
+1%
|
|
|
16
|
Perceptive Advisors
New York
|
$58.2M
|
–
|
–
|
–
|
|
|
17
|
AllianceBernstein
Nashville,
Tennessee
|
$54.1M
|
+$1.54M
|
+63,323
|
+4%
|
|
|
18
|
Alphabet Inc
Mountain View,
California
|
$47M
|
+$111K
|
+4,580
|
+0.3%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$40.5M
|
+$1.15M
|
+47,461
|
+4%
|
|
|
20
|
|
$28.1M
|
+$2.86M
|
+117,926
|
+14%
|
|
|
21
|
|
$21M
|
-$1.21M
|
-50,000
|
-7%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$19.5M
|
-$826K
|
-34,039
|
-5%
|
|
|
23
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$18M
|
+$94.6K
|
+3,900
|
+0.7%
|
|
|
24
|
Bessemer Group
Woodbridge,
New Jersey
|
$17.5M
|
–
|
–
|
–
|
|
|
25
|
|
$17.2M
|
-$990K
|
-40,811
|
-7%
|
|
