|
1
|
SB Investment Advisers (UK)
London,
United Kingdom
|
$522M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$376M
|
+$238M
|
+16,414,682
|
+444%
|
|
|
3
|
|
$300M
|
+$23.5M
|
+1,616,666
|
+11%
|
|
|
4
|
|
$286M
|
+$33.6M
|
+2,312,903
|
+18%
|
|
|
5
|
Perceptive Advisors
New York
|
$264M
|
+$63.2M
|
+4,355,046
|
+45%
|
|
|
6
|
Commodore Capital
New York
|
$225M
|
-$72.6M
|
-5,000,000
|
-29%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$189M
|
+$56.5M
|
+3,891,836
|
+62%
|
|
|
8
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$168M
|
+$22.9M
|
+1,576,958
|
+21%
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$144M
|
+$84M
|
+5,783,569
|
+300%
|
|
|
10
|
Nextech Invest
Zurich,
Switzerland
|
$127M
|
+$18.1M
|
+1,250,000
|
+23%
|
|
|
11
|
Bellevue Group
Kuesnacht,
Switzerland
|
$116M
|
-$23.4M
|
-1,609,272
|
-21%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$88.4M
|
+$17.7M
|
+1,215,940
|
+35%
|
|
|
13
|
TCG Crossover Management
Palo Alto,
California
|
$80M
|
–
|
–
|
–
|
|
|
14
|
|
$72.1M
|
+$35.1M
|
+2,419,068
|
+169%
|
|
|
15
|
Siren LLC
Greenwich,
Connecticut
|
$68.3M
|
+$53M
|
+3,650,000
|
New
|
|
|
16
|
|
$63.8M
|
+$12.6M
|
+866,840
|
+34%
|
|
|
17
|
Westfield Capital Management
Boston,
Massachusetts
|
$62.6M
|
+$48.5M
|
+3,343,496
|
New
|
|
|
18
|
Kynam Capital Management
Princeton,
New Jersey
|
$61.7M
|
+$27.2M
|
+1,875,741
|
+132%
|
|
|
19
|
Dimensional Fund Advisors
Austin,
Texas
|
$58.5M
|
+$2.72M
|
+187,028
|
+6%
|
|
|
20
|
Spruce Street Capital
New York
|
$55.8M
|
–
|
–
|
–
|
|
|
21
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$54.1M
|
+$14.9M
|
+1,029,220
|
+55%
|
|
|
22
|
Baker Bros. Advisors
New York
|
$52.9M
|
+$24.2M
|
+1,666,666
|
+144%
|
|
|
23
|
Bank of America
Charlotte,
North Carolina
|
$50.4M
|
+$11M
|
+757,413
|
+39%
|
|
|
24
|
MPM BioImpact
Boston,
Massachusetts
|
$45.2M
|
+$814K
|
+56,086
|
+2%
|
|
|
25
|
Arrowstreet Capital
Boston,
Massachusetts
|
$41.9M
|
+$22.8M
|
+1,570,640
|
+235%
|
|
