Regulus Therapeutics
RGLS
RGLS was delisted on the 24th of June, 2025.
103 hedge funds and large institutions have $299M invested in Regulus Therapeutics in 2015 Q4 according to their latest regulatory filings, with 20 funds opening new positions, 34 increasing their positions, 29 reducing their positions, and 8 closing their positions.
1,559% more call options, than puts
Call options by funds: $12.7M | Put options by funds: $768K
150% more first-time investments, than exits
New positions opened: 20 | Existing positions closed: 8
50% more funds holding in top 10
Funds holding in top 10: 2 → 3 (+1)
32% more capital invested
Capital invested by funds: $226M → $299M (+$72.7M)
17% more repeat investments, than reductions
Existing positions increased: 34 | Existing positions reduced: 29
12% more funds holding
Funds holding: 92 → 103 (+11)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
UBS AM
Chicago,
Illinois
|
+$3.74M |
| 2 |
CPIM
Columbia Partners Investment Management
Alexandria,
Virginia
|
+$3.54M |
| 3 |
OAM
Oxford Asset Management
Oxford,
United Kingdom
|
+$2.18M |
| 4 |
TI
Trexquant Investment
Stamford,
Connecticut
|
+$940K |
| 5 |
DCM
Driehaus Capital Management
Chicago,
Illinois
|
+$782K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
CAM
Cormorant Asset Management
Boston,
Massachusetts
|
-$7.23M |
| 2 |
RCM
RA Capital Management
Boston,
Massachusetts
|
-$4.65M |
| 3 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$2.51M |
| 4 |
OIM
Oracle Investment Management
Greenwich,
Connecticut
|
-$2.45M |
| 5 |
SM
Sabby Management
Miami Beach,
Florida
|
-$1.22M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
101
Bank of Montreal
Toronto,
Ontario, Canada
| $1K | – | – | – |
|
|
IWMPD
102
Integrated Wealth Management (Palm Desert)
Palm Desert,
California
| $1K | – | – | – |
|
103
Manulife (Manufacturers Life Insurance)
Canada,
Ontario, Canada
| $175 | +$4.01K | +4 | +2% |
|
|
OIM
104
Oracle Investment Management
Greenwich,
Connecticut
| – | -$2.45M | -3,121 | Closed |
|
|
AC
105
Amici Capital
New York
| – | -$491K | -625 | Closed |
|
106
AQR Capital Management
Greenwich,
Connecticut
| – | -$335K | -426 | Closed |
|
107
Federated Hermes
Pittsburgh,
Pennsylvania
| – | -$164K | -208 | Closed |
|
|
QIM
108
Quantitative Investment Management
Charlottesville,
Virginia
| – | -$110K | -141 | Closed |
|
|
VKH
109
Virtu KCG Holdings
New York
| – | -$81K | -103 | Closed |
|
110
SG Americas Securities
New York
| – | -$68K | -87 | Closed |
|
111
Creative Planning
Overland Park,
Kansas
| – | -$16K | -20 | Closed |
|
RGLS Hedge Fund Activity: Q4 2015 in Review
103 of the 3,812 institutional investors tracked by Wall St. Rank reported a position in Regulus Therapeutics (RGLS) for Q4 2015, worth a combined $299M — up 32% from $226M a quarter earlier.
Buyers outnumbered sellers: 20 funds opened new RGLS positions and 8 closed out — a net gain of 12 holders — while 34 added to existing stakes and 29 trimmed.
The largest buyer was UBS AM, adding an estimated $3.74M. The largest seller was Cormorant Asset Management, cutting an estimated $7.23M.
- 103 institutional investors held Regulus Therapeutics (RGLS) as of Q4 2015, up from 92 in Q3 2015.
- Funds reported $299M of Regulus Therapeutics stock for Q4 2015, up 32% quarter-over-quarter.
- 20 funds opened new Regulus Therapeutics positions in Q4 2015 and 8 closed out, a net change of +12 holders.
- The largest Regulus Therapeutics buyer in Q4 2015 was UBS AM, an estimated $3.74M added.
- The largest Regulus Therapeutics seller in Q4 2015 was Cormorant Asset Management, an estimated $7.23M sold.
Based on aggregated 13F filings for Q4 2015.