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uniQure

253 hedge funds and large institutions have $3.02B invested in uniQure in 2026 Q2 according to their latest regulatory filings, with 91 funds opening new positions, 86 increasing their positions, 58 reducing their positions, and 48 closing their positions.

New
Increased
Maintained
Reduced
Closed

371% more call options, than puts

Call options by funds: $516M | Put options by funds: $110M

211% more capital invested

Capital invested by funds: $971M → $3.02B (+$2.05B)

90% more first-time investments, than exits

New positions opened: 91 | Existing positions closed: 48

48% more repeat investments, than reductions

Existing positions increased: 86 | Existing positions reduced: 58

19% more funds holding

Funds holding: 213253 (+40)

8.17% more ownership

Funds ownership: 95.44%103.61% (+8.2%)

Holders
253
Holders Change
+40
Holders Change %
+18.78%
% of All Funds
3.06%
Holding in Top 10
6
Holding in Top 10 Change
+6
Holding in Top 10 Change %
% of All Funds
0.07%
New
91
Increased
86
Reduced
58
Closed
48
Calls
$516M
Puts
$110M
Net Calls
+$407M
Net Calls Change
+$167M
Name Holding Trade Value Shares
Change
Change in
Stake
Squarepoint
51
Squarepoint
New York
$12.9M -$1.72M -65,683 -19%
Franklin Resources
52
Franklin Resources
California
$11.3M -$6.17M -235,594 -49%
New York State Common Retirement Fund
53
New York State Common Retirement Fund
New York
$11.2M +$2.53M +96,689 +66%
NAMI
54
Nomura Asset Management International
Pennsylvania
$10M -$1.07M -40,711 -16%
Northern Trust
55
Northern Trust
Illinois
$9.81M +$1.13M +42,976 +25%
PHP
56
Parkman Healthcare Partners
Connecticut
$9.59M +$34.8K +1,328 +0.6%
D.E. Shaw & Co
57
D.E. Shaw & Co
New York
$9.56M +$1.23M +46,915 +29%
DC
58
Diametric Capital
Massachusetts
$9.08M +$4.68M +178,847 +972%
PMAM
59
Picton Mahoney Asset Management
Ontario, Canada
$8.35M +$4.74M +181,215 New
AAA
60
Affinity Asset Advisors
New York
$8.06M +$4.58M +175,000 New
TI
61
Trexquant Investment
Connecticut
$7.88M +$4.48M +171,149 New
PA
62
Perceptive Advisors
New York
$7.74M +$4.4M +168,000 New
FCM
63
Freshford Capital Management
New York
$7.46M +$4.24M +161,855 New
FPC
64
Flax Pond Capital
Massachusetts
$7.22M +$123K +4,695 +3%
Ameriprise
65
Ameriprise
Minnesota
$7.02M +$2.49M +95,210 +167%
CC
66
Casdin Capital
New York
$6.91M +$3.93M +150,000 New
Wells Fargo
67
Wells Fargo
California
$6.91M +$1.22M +46,525 +45%
HWAM
68
Hennion & Walsh Asset Management
New Jersey
$6.55M +$1.93M +73,566 +107%
Vanguard Portfolio Management
69
Vanguard Portfolio Management
Pennsylvania
$6.5M +$3.69M +141,093 New
HF
70
HRT Financial
New York
$6.25M +$3.55M +135,641 New
Citigroup
71
Citigroup
New York
$5.89M -$10.6M -403,941 -76%
Envestnet Asset Management
72
Envestnet Asset Management
Illinois
$5.83M +$786K +30,017 +31%
Royal Bank of Canada
73
Royal Bank of Canada
Ontario, Canada
$5.72M +$429K +16,405 +15%
SPS
74
Susquehanna Portfolio Strategies
Pennsylvania
$5.61M -$448K -17,100 -12%
Hudson Bay Capital Management
75
Hudson Bay Capital Management
Connecticut
$5.53M -$1.01M -38,500 -24%

QURE Hedge Fund Activity: Q2 2026 in Review

253 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in uniQure (QURE) for Q2 2026, worth a combined $3.02B — up 211% from $971M a quarter earlier.

Buyers outnumbered sellers: 91 funds opened new QURE positions and 48 closed out — a net gain of 43 holders — while 86 added to existing stakes and 58 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $53.1M. The largest seller was Aberdeen Group, cutting an estimated $64.4M.

  • 253 institutional investors held uniQure (QURE) as of Q2 2026, up from 213 in Q1 2026.
  • Funds reported $3.02B of uniQure stock for Q2 2026, up 211% quarter-over-quarter.
  • 91 funds opened new uniQure positions in Q2 2026 and 48 closed out, a net change of +43 holders.
  • The largest uniQure buyer in Q2 2026 was JP Morgan Chase, an estimated $53.1M added.
  • The largest uniQure seller in Q2 2026 was Aberdeen Group, an estimated $64.4M sold.

Based on aggregated 13F filings for Q2 2026.