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uniQure
QURE

213 hedge funds and large institutions have $971M invested in uniQure in 2026 Q1 according to their latest regulatory filings, with 47 funds opening new positions, 72 increasing their positions, 61 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

561% more call options, than puts

Call options by funds: $283M | Put options by funds: $42.8M

18% more repeat investments, than reductions

Existing positions increased: 72 | Existing positions reduced: 61

10% less first-time investments, than exits

New positions opened: 47 | Existing positions closed: 52

3.88% less ownership

Funds ownership: 99.32% → 95.44% (-3.9%)

5% less funds holding

Funds holding: 225 → 213 (-12)

34% less capital invested

Capital invested by funds: $1.48B → $971M (-$510M)

100% less funds holding in top 10

Funds holding in top 10: 3 → 0 (-3)

Holders
213
Holders Change
-12
Holders Change %
-5.33%
% of All Funds
2.61%
Holding in Top 10
–
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-100%
% of All Funds
–
New
47
Increased
72
Reduced
61
Closed
52
Calls
$283M
Puts
$42.8M
Net Calls
+$240M
Net Calls Change
+$75.3M

Top Buyers

Rank Fund Capital Flow
1
Aberdeen Group
Aberdeen Group
United Kingdom
+$33M
2
O
OrbiMed
New York
+$28.3M
3
TSC
Two Seas Capital
New York
+$26.3M
4
Two Sigma Investments
Two Sigma Investments
New York
+$24.8M
5
SL
Siren LLC
Connecticut
+$20.2M

Top Sellers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
-$91.1M
2
SCM
Suvretta Capital Management
New York
-$29.1M
3
AGP
Artia Global Partners
Florida
-$24.5M
4
RI
RTW Investments
New York
-$22.8M
5
State Street
State Street
Massachusetts
-$19.7M
Name Holding Trade Value Shares
Change 		Change in
Stake
NCM
51
Nantahala Capital Management
Connecticut
$3.88M -$9.36M -462,220 -66%
Simplex Trading
52
Simplex Trading
Illinois
$3.79M +$2.45M +121,094 +109%
PHP
53
Parkman Healthcare Partners
Connecticut
$3.38M -$1.02M -50,540 -20%
Group One Trading
54
Group One Trading
Illinois
$2.93M +$3.62M +179,000 New
Northern Trust
55
Northern Trust
Illinois
$2.78M +$23.1K +1,139 +0.7%
Barclays
56
Barclays
United Kingdom
$2.74M -$852K -42,058 -20%
D.E. Shaw & Co
57
D.E. Shaw & Co
New York
$2.63M +$582K +28,758 +22%
Hudson Bay Capital Management
58
Hudson Bay Capital Management
Connecticut
$2.59M +$668K +33,000 +26%
FPC
59
Flax Pond Capital
Massachusetts
$2.49M +$112K +5,533 +4%
CDMG
60
Creek Drive Management Group
California
$2.45M +$3.04M +150,000 New
New York State Common Retirement Fund
61
New York State Common Retirement Fund
New York
$2.41M – – –
Assenagon Asset Management
62
Assenagon Asset Management
Luxembourg
$2.4M -$9.32M -460,174 -76%
SPS
63
Susquehanna Portfolio Strategies
Pennsylvania
$2.27M +$2.23M +110,261 +384%
Marshall Wace
64
Marshall Wace
United Kingdom
$2.01M +$2.06M +101,577 +480%
MCM
65
Moore Capital Management
New York
$2M +$956K +47,222 +63%
TC
66
Tejara Capital
United Kingdom
$2M +$1.62M +80,092 +191%
KPF
67
K2 Principal Fund
Ontario, Canada
$1.94M +$2.4M +118,600 New
NFT
68
Nan Fung Trinity
Hong Kong
$1.89M – – –
YIH
69
Y-Intercept (HK)
Hong Kong
$1.86M +$1.38M +68,174 +149%
PHS
70
Pekin Hardy Strauss
Illinois
$1.84M +$1.69M +83,275 +284%
BHCM
71
Brevan Howard Capital Management
Jersey
$1.78M +$2.2M +108,632 New
Royal Bank of Canada
72
Royal Bank of Canada
Ontario, Canada
$1.76M +$450K +22,248 +26%
PBM
73
Propel Bio Management
California
$1.71M +$2.12M +104,772 New
Wells Fargo
74
Wells Fargo
California
$1.69M +$672K +33,210 +47%
BC
75
Birchview Capital
Vermont
$1.65M +$1.42M +69,908 +227%
1 2
3
4 5

QURE Hedge Fund Activity: Q1 2026 in Review

213 of the 8,172 institutional investors tracked by Wall St. Rank reported a position in uniQure (QURE) for Q1 2026, worth a combined $971M — down 34% from $1.48B a quarter earlier.

Sellers outnumbered buyers: 52 funds closed out of QURE and 47 opened new positions — a net loss of 5 holders — while 61 trimmed existing stakes and 72 added.

The largest buyer was Aberdeen Group, adding an estimated $33M. The largest seller was Fidelity Investments, cutting an estimated $91.1M.

  • 213 institutional investors held uniQure (QURE) as of Q1 2026, down from 225 in Q4 2025.
  • Funds reported $971M of uniQure stock for Q1 2026, down 34% quarter-over-quarter.
  • 47 funds opened new uniQure positions in Q1 2026 and 52 closed out, a net change of -5 holders.
  • The largest uniQure buyer in Q1 2026 was Aberdeen Group, an estimated $33M added.
  • The largest uniQure seller in Q1 2026 was Fidelity Investments, an estimated $91.1M sold.

Based on aggregated 13F filings for Q1 2026.