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uniQure
QURE

213 hedge funds and large institutions have $971M invested in uniQure in 2026 Q1 according to their latest regulatory filings, with 47 funds opening new positions, 72 increasing their positions, 61 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

561% more call options, than puts

Call options by funds: $283M | Put options by funds: $42.8M

18% more repeat investments, than reductions

Existing positions increased: 72 | Existing positions reduced: 61

10% less first-time investments, than exits

New positions opened: 47 | Existing positions closed: 52

3.88% less ownership

Funds ownership: 99.32% → 95.44% (-3.9%)

5% less funds holding

Funds holding: 225 → 213 (-12)

34% less capital invested

Capital invested by funds: $1.48B → $971M (-$510M)

100% less funds holding in top 10

Funds holding in top 10: 3 → 0 (-3)

Holders
213
Holders Change
-12
Holders Change %
-5.33%
% of All Funds
2.61%
Holding in Top 10
–
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-100%
% of All Funds
–
New
47
Increased
72
Reduced
61
Closed
52
Calls
$283M
Puts
$42.8M
Net Calls
+$240M
Net Calls Change
+$75.3M

Top Buyers

Rank Fund Capital Flow
1
Aberdeen Group
Aberdeen Group
United Kingdom
+$33M
2
O
OrbiMed
New York
+$28.3M
3
TSC
Two Seas Capital
New York
+$26.3M
4
Two Sigma Investments
Two Sigma Investments
New York
+$24.8M
5
SL
Siren LLC
Connecticut
+$20.2M

Top Sellers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
-$91.1M
2
SCM
Suvretta Capital Management
New York
-$29.1M
3
AGP
Artia Global Partners
Florida
-$24.5M
4
RI
RTW Investments
New York
-$22.8M
5
State Street
State Street
Massachusetts
-$19.7M
Name Holding Trade Value Shares
Change 		Change in
Stake
Jane Street
26
Jane Street
New York
$10.4M +$12.9M +635,995 New
FTM
27
First Turn Management
California
$10.1M +$5.95M +293,834 +91%
VC
28
Voss Capital
Texas
$9.89M +$8M +395,000 +188%
Citigroup
29
Citigroup
New York
$8.7M +$7.03M +347,120 +188%
NNPTE
30
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne
Poland
$8.53M – – –
RAM
31
Readystate Asset Management
Illinois
$8.25M +$2.9M +143,142 +40%
6CM
32
683 Capital Management
New York
$8.17M +$2.33M +115,050 +30%
CCM
33
Catalio Capital Management
New York
$8.03M +$4.11M +202,771 +70%
UBS Group
34
UBS Group
Switzerland
$7.98M -$73.2K -3,616 -0.7%
PFM
35
Privium Fund Management
Netherlands
$7.95M +$1.42M +70,250 +17%
Franklin Resources
36
Franklin Resources
California
$7.86M -$5.38M -265,736 -36%
MCO
37
MAK Capital One
New York
$7.21M +$8.93M +441,205 New
ECM
38
ExodusPoint Capital Management
New York
$7.14M +$7.34M +362,692 +492%
MCM
39
Massar Capital Management
Connecticut
$6.97M +$7.81M +385,500 +951%
Citadel Advisors
40
Citadel Advisors
Florida
$6.61M -$1.31M -64,735 -14%
Charles Schwab
41
Charles Schwab
California
$6.15M +$263K +12,974 +4%
Morgan Stanley
42
Morgan Stanley
New York
$5.99M -$7.1M -350,810 -49%
VPC
43
Vestal Point Capital
New York
$5.87M +$7.27M +358,996 New
Squarepoint
44
Squarepoint
New York
$5.66M +$3.44M +169,983 +97%
Vanguard Fiduciary Trust
45
Vanguard Fiduciary Trust
Pennsylvania
$5.44M +$6.73M +332,523 New
CM
46
Caption Management
Oklahoma
$4.96M +$2.55M +125,954 +71%
EGM
47
Engineers Gate Manager
New York
$4.9M +$5.19M +256,401 +591%
KCM
48
Kalehua Capital Management
Texas
$4.76M +$5.89M +291,109 New
NAMI
49
Nomura Asset Management International
Pennsylvania
$4.22M – – –
Bank of America
50
Bank of America
North Carolina
$4.04M -$1.67M -82,674 -25%
1
2
3 4 5

QURE Hedge Fund Activity: Q1 2026 in Review

213 of the 8,172 institutional investors tracked by Wall St. Rank reported a position in uniQure (QURE) for Q1 2026, worth a combined $971M — down 34% from $1.48B a quarter earlier.

Sellers outnumbered buyers: 52 funds closed out of QURE and 47 opened new positions — a net loss of 5 holders — while 61 trimmed existing stakes and 72 added.

The largest buyer was Aberdeen Group, adding an estimated $33M. The largest seller was Fidelity Investments, cutting an estimated $91.1M.

  • 213 institutional investors held uniQure (QURE) as of Q1 2026, down from 225 in Q4 2025.
  • Funds reported $971M of uniQure stock for Q1 2026, down 34% quarter-over-quarter.
  • 47 funds opened new uniQure positions in Q1 2026 and 52 closed out, a net change of -5 holders.
  • The largest uniQure buyer in Q1 2026 was Aberdeen Group, an estimated $33M added.
  • The largest uniQure seller in Q1 2026 was Fidelity Investments, an estimated $91.1M sold.

Based on aggregated 13F filings for Q1 2026.