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Prime Medicine
PRME

Overview Fund Activity

123 hedge funds and large institutions have $120M invested in Prime Medicine in 2025 Q1 according to their latest regulatory filings, with 21 funds opening new positions, 41 increasing their positions, 35 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
123
Holders Change
-7
Holders Change %
-5.38%
% of All Funds
1.67%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
21
Increased
41
Reduced
35
Closed
27
Calls
$120K
Puts
$237K
Net Calls
-$117K
Net Calls Change
+$193K

Top Buyers

1
Renaissance Technologies
Renaissance Technologies
New York
+$891K
2
AQR Capital Management
AQR Capital Management
Connecticut
+$453K
3
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$329K
4
GCP
GSA Capital Partners
United Kingdom
+$275K
5
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$210K

Top Sellers

1
AIM
ARK Investment Management
Florida
-$4.09M
2
WHG
Westwood Holdings Group
Texas
-$2.58M
3
Walleye Capital
Walleye Capital
New York
-$1.18M
4
Bank of America
Bank of America
North Carolina
-$632K
5
BlackRock
BlackRock
New York
-$435K
Name Holding Trade Value Shares
Change 		Shares
Change %
Morgan Stanley
26
Morgan Stanley
New York
$707K +$87.4K +43,900 +14%
Two Sigma Investments
27
Two Sigma Investments
New York
$515K +$184K +92,571 +56%
Goldman Sachs
28
Goldman Sachs
New York
$500K -$339K -170,499 -40%
AQR Capital Management
29
AQR Capital Management
Connecticut
$485K +$453K +227,749 +1,419%
CCC
30
Chelsea Counsel Company
California
$414K +$42.6K +21,430 +11%
NL
31
Nuveen LLC
North Carolina
$374K +$374K +59,402 New
Bank of New York Mellon
32
Bank of New York Mellon
New York
$310K +$52.7K +26,478 +20%
GCP
33
GSA Capital Partners
United Kingdom
$305K +$275K +137,962 +901%
Susquehanna International Group
34
Susquehanna International Group
Pennsylvania
$284K +$210K +105,567 +285%
Deutsche Bank
35
Deutsche Bank
Germany
$252K +$91.6K +46,011 +57%
Fidelity International
36
Fidelity International
Bermuda
$241K – – –
UBS Group
37
UBS Group
Switzerland
$234K -$200K -100,506 -46%
Bank of America
38
Bank of America
North Carolina
$225K -$632K -317,687 -74%
PWM
39
Palumbo Wealth Management
New York
$190K +$190K +95,462 New
Wells Fargo
40
Wells Fargo
California
$181K -$10.7K -5,362 -6%
IEFM
41
IQ EQ Fund Management
Ireland
$179K +$58.1K +29,185 +48%
GAA
42
Green Alpha Advisors
Colorado
$166K +$37.9K +19,061 +30%
RhumbLine Advisers
43
RhumbLine Advisers
Massachusetts
$163K +$19.8K +9,944 +14%
VAS
44
Vestmark Advisory Solutions
Massachusetts
$156K -$65.4K -32,866 -29%
AllianceBernstein
45
AllianceBernstein
Tennessee
$151K – – –
Barclays
46
Barclays
United Kingdom
$143K -$52.5K -26,197 -27%
Tudor Investment Corp
47
Tudor Investment Corp
Connecticut
$120K +$120K +60,368 New
IIM
48
INTECH Investment Management
Florida
$109K +$48.8K +24,542 +81%
VIA
49
Virtus Investment Advisers
Connecticut
$109K +$109K +54,535 New
Two Sigma Advisers
50
Two Sigma Advisers
New York
$107K +$21.3K +10,700 +25%
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