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Prime Medicine
PRME

83 hedge funds and large institutions have $472M invested in Prime Medicine in 2023 Q3 according to their latest regulatory filings, with 11 funds opening new positions, 35 increasing their positions, 15 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed

870% more call options, than puts

Call options by funds: $97K | Put options by funds: $10K

133% more repeat investments, than reductions

Existing positions increased: 35 | Existing positions reduced: 15

83% more first-time investments, than exits

New positions opened: 11 | Existing positions closed: 6

5% more funds holding

Funds holding: 79 → 83 (+4)

3.45% more ownership

Funds ownership: 47.45% → 50.89% (+3.4%)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

30% less capital invested

Capital invested by funds: $676M → $472M (-$203M)

Holders
83
Holders Change
+4
Holders Change %
+5.06%
% of All Funds
1.32%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
11
Increased
35
Reduced
15
Closed
6
Calls
$97K
Puts
$10K
Net Calls
+$87K
Net Calls Change
+$87K

Top Buyers

Rank Fund Capital Flow
1
State Street
State Street
Massachusetts
+$14M
2
Vanguard Group
Vanguard Group
Pennsylvania
+$8.02M
3
Sumitomo Mitsui Trust Group
Sumitomo Mitsui Trust Group
Japan
+$7.42M
4
NAMA
Nikko Asset Management Americas
New York
+$7.41M
5
BlackRock
BlackRock
New York
+$5.78M

Top Sellers

Rank Fund Capital Flow
1
Jane Street
Jane Street
New York
-$5.82M
2
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$5.77M
3
Millennium Management
Millennium Management
New York
-$3.76M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$2.08M
5
Fidelity Investments
Fidelity Investments
Massachusetts
-$1.52M
Name Holding Trade Value Shares
Change 		Change in
Stake
Janus Henderson Group
26
Janus Henderson Group
United Kingdom
$1.15M -$5.77M -443,908 -79%
Bank of New York Mellon
27
Bank of New York Mellon
New York
$1.1M +$158K +12,176 +12%
N
28
Nuveen
North Carolina
$1.02M -$211K -16,273 -13%
TD Asset Management
29
TD Asset Management
Ontario, Canada
$997K +$487K +37,471 +56%
Two Sigma Investments
30
Two Sigma Investments
New York
$887K +$1.21M +92,993 New
Barclays
31
Barclays
United Kingdom
$621K +$744K +57,261 +727%
Manulife (Manufacturers Life Insurance)
32
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$617K +$81.3K +6,259 +11%
Goldman Sachs
33
Goldman Sachs
New York
$562K +$765K +58,911 New
Citigroup
34
Citigroup
New York
$536K +$546K +42,032 +297%
RhumbLine Advisers
35
RhumbLine Advisers
Massachusetts
$486K +$50.6K +3,896 +8%
UBS Group
36
UBS Group
Switzerland
$418K -$718K -55,267 -56%
Morgan Stanley
37
Morgan Stanley
New York
$408K -$197K -15,138 -26%
GAA
38
Green Alpha Advisors
Colorado
$361K +$330K +25,429 +205%
BM
39
Brandywine Managers
Delaware
$315K – – –
AllianceBernstein
40
AllianceBernstein
Tennessee
$304K +$68.8K +5,300 +20%
Wells Fargo
41
Wells Fargo
California
$299K +$195K +15,020 +92%
JP Morgan Chase
42
JP Morgan Chase
New York
$258K -$47.5K -3,658 -12%
Mirae Asset Global Investments
43
Mirae Asset Global Investments
South Korea
$220K +$53.8K +4,145 +22%
PA
44
Profund Advisors
Maryland
$210K +$286K +21,995 New
OC
45
Oppenheimer & Co
New York
$205K +$79.9K +6,152 +40%
MIM
46
MetLife Investment Management
New Jersey
$203K – – –
HighTower Advisors
47
HighTower Advisors
Illinois
$201K -$299 -23 -0.1%
Deutsche Bank
48
Deutsche Bank
Germany
$196K +$35.6K +2,743 +15%
AIG
49
American International Group
New York
$188K +$9.13K +703 +4%
PCM
50
Penserra Capital Management
California
$176K +$135K +10,361 +128%
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PRME Hedge Fund Activity: Q3 2023 in Review

83 of the 6,301 institutional investors tracked by Wall St. Rank reported a position in Prime Medicine (PRME) for Q3 2023, worth a combined $472M — down 30% from $676M a quarter earlier.

Buyers outnumbered sellers: 11 funds opened new PRME positions and 6 closed out — a net gain of 5 holders — while 35 added to existing stakes and 15 trimmed.

The largest buyer was State Street, adding an estimated $14M. The largest seller was Jane Street, exiting entirely with an estimated $5.82M sold.

  • 83 institutional investors held Prime Medicine (PRME) as of Q3 2023, up from 79 in Q2 2023.
  • Funds reported $472M of Prime Medicine stock for Q3 2023, down 30% quarter-over-quarter.
  • 11 funds opened new Prime Medicine positions in Q3 2023 and 6 closed out, a net change of +5 holders.
  • The largest Prime Medicine buyer in Q3 2023 was State Street, an estimated $14M added.
  • The largest Prime Medicine seller in Q3 2023 was Jane Street, an estimated $5.82M sold.

Based on aggregated 13F filings for Q3 2023.