Opko Health
OPK
222 hedge funds and large institutions have $270M invested in Opko Health in 2025 Q2 according to their latest regulatory filings, with 17 funds opening new positions, 56 increasing their positions, 66 reducing their positions, and 48 closing their positions.
562% more call options, than puts
Call options by funds: $3.77M | Put options by funds: $569K
10.18% less ownership
Funds ownership: 36.05% → 25.87% (-10%)
13% less funds holding
Funds holding: 255 → 222 (-33)
15% less repeat investments, than reductions
Existing positions increased: 56 | Existing positions reduced: 66
33% less capital invested
Capital invested by funds: $401M → $270M (-$131M)
65% less first-time investments, than exits
New positions opened: 17 | Existing positions closed: 48
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Vanguard Group
Malvern,
Pennsylvania
|
+$11.9M |
| 2 |
BlackRock
New York
|
+$5.26M |
| 3 |
UBS Group
Zurich,
Switzerland
|
+$4.51M |
| 4 |
Geode Capital Management
Boston,
Massachusetts
|
+$2.73M |
| 5 |
WCM
Whitefort Capital Management
New York
|
+$2.43M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
SC
Sculptor Capital
New York
|
-$21.1M |
| 2 |
DM
Deerfield Management
New York
|
-$11.5M |
| 3 |
WAM
Weiss Asset Management
Boston,
Massachusetts
|
-$8.8M |
| 4 |
D.E. Shaw & Co
New York
|
-$7.85M |
| 5 |
Millennium Management
New York
|
-$7.78M |
OPK Hedge Fund Activity: Q2 2025 in Review
222 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Opko Health (OPK) for Q2 2025, worth a combined $270M — down 33% from $401M a quarter earlier.
Sellers outnumbered buyers: 48 funds closed out of OPK and 17 opened new positions — a net loss of 31 holders — while 66 trimmed existing stakes and 56 added.
The largest buyer was Vanguard Group, adding an estimated $11.9M. The largest seller was Sculptor Capital, exiting entirely with an estimated $21.1M sold.
- 222 institutional investors held Opko Health (OPK) as of Q2 2025, down from 255 in Q1 2025.
- Funds reported $270M of Opko Health stock for Q2 2025, down 33% quarter-over-quarter.
- 17 funds opened new Opko Health positions in Q2 2025 and 48 closed out, a net change of -31 holders.
- The largest Opko Health buyer in Q2 2025 was Vanguard Group, an estimated $11.9M added.
- The largest Opko Health seller in Q2 2025 was Sculptor Capital, an estimated $21.1M sold.
Based on aggregated 13F filings for Q2 2025.