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Opko Health

233 hedge funds and large institutions have $304M invested in Opko Health in 2025 Q3 according to their latest regulatory filings, with 29 funds opening new positions, 77 increasing their positions, 53 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,936% more call options, than puts

Call options by funds: $4.26M | Put options by funds: $209K

93% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 15

45% more repeat investments, than reductions

Existing positions increased: 77 | Existing positions reduced: 53

12% more capital invested

Capital invested by funds: $270M → $304M (+$33.2M)

5% more funds holding

Funds holding: 222233 (+11)

1.14% less ownership

Funds ownership: 25.87%24.73% (-1.1%)

Holders
233
Holders Change
+11
Holders Change %
+4.95%
% of All Funds
3.06%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
29
Increased
77
Reduced
53
Closed
15
Calls
$4.26M
Puts
$209K
Net Calls
+$4.05M
Net Calls Change
+$847K
Name Holding Trade Value Shares
Change
Change in
Stake
RCMNY
1
Rubric Capital Management (New York)
New York
$74.1M
Vanguard Group
2
Vanguard Group
Pennsylvania
$58.2M -$965K -702,817 -2%
BlackRock
3
BlackRock
New York
$51.4M +$2.37M +1,722,902 +5%
Geode Capital Management
4
Geode Capital Management
Massachusetts
$17M +$781K +568,872 +5%
State Street
5
State Street
Massachusetts
$13.9M +$571K +416,100 +5%
WCM
6
Whitefort Capital Management
New York
$7.59M +$4.29M +3,125,800 +176%
UBS Group
7
UBS Group
Switzerland
$7.4M -$1.3M -944,096 -17%
Charles Schwab
8
Charles Schwab
California
$5.84M +$575K +418,558 +12%
Northern Trust
9
Northern Trust
Illinois
$5.67M +$241K +175,574 +5%
AQR Capital Management
10
AQR Capital Management
Connecticut
$4.45M +$2.66M +1,937,516 +207%
Goldman Sachs
11
Goldman Sachs
New York
$3.7M -$595K -433,520 -15%
AIC
12
AWM Investment Company
New York
$3.41M +$275K +200,000 +10%
Dimensional Fund Advisors
13
Dimensional Fund Advisors
Texas
$2.58M -$360K -262,315 -14%
YDMI
14
Y.D. More Investments
Israel
$2.24M -$40.9K -29,781 -2%
WGS
15
Washington Growth Strategies
District of Columbia
$2.1M
PI
16
PFG Investments
New York
$2.07M +$99.2K +72,250 +6%
Bank of America
17
Bank of America
North Carolina
$2.04M -$814K -592,957 -31%
Bank of New York Mellon
18
Bank of New York Mellon
New York
$1.98M +$176K +127,962 +11%
Two Sigma Investments
19
Two Sigma Investments
New York
$1.95M -$798K -581,100 -32%
VOYA Investment Management
20
VOYA Investment Management
Georgia
$1.89M -$139K -101,559 -8%
WAM
21
Weiss Asset Management
Massachusetts
$1.75M -$4.98M -3,626,221 -76%
Invesco
22
Invesco
Georgia
$1.58M -$485K -353,484 -26%
TC
23
Tejara Capital
United Kingdom
$1.36M -$93.6K -68,149 -7%
Swiss National Bank
24
Swiss National Bank
Switzerland
$1.31M +$369K +268,400 +46%
N
25
Nuveen
North Carolina
$1.3M -$391K -284,721 -25%

OPK Hedge Fund Activity: Q3 2025 in Review

233 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Opko Health (OPK) for Q3 2025, worth a combined $304M — up 12% from $270M a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new OPK positions and 15 closed out — a net gain of 14 holders — while 77 added to existing stakes and 53 trimmed.

The largest buyer was Whitefort Capital Management, adding an estimated $4.29M. The largest seller was Weiss Asset Management, cutting an estimated $4.98M.

  • 233 institutional investors held Opko Health (OPK) as of Q3 2025, up from 222 in Q2 2025.
  • Funds reported $304M of Opko Health stock for Q3 2025, up 12% quarter-over-quarter.
  • 29 funds opened new Opko Health positions in Q3 2025 and 15 closed out, a net change of +14 holders.
  • The largest Opko Health buyer in Q3 2025 was Whitefort Capital Management, an estimated $4.29M added.
  • The largest Opko Health seller in Q3 2025 was Weiss Asset Management, an estimated $4.98M sold.

Based on aggregated 13F filings for Q3 2025.