Vanguard Group’s Opko Health OPK Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2025
Q4
$40.9M Sell
32,457,788
-5,078,109
-14% -$7.07M ﹤0.01% 2276
2025
Q3
$58.2M Sell
37,535,897
-702,817
-2% -$965K ﹤0.01% 2083
2025
Q2
$50.5M Buy
38,238,714
+8,738,643
+30% +$11.9M ﹤0.01% 2114
2025
Q1
$49M Buy
29,500,071
+293,740
+1% +$484K ﹤0.01% 2100
2024
Q4
$42.9M Sell
29,206,331
-11,819
-0% -$18.1K ﹤0.01% 2231
2024
Q3
$43.5M Buy
29,218,150
+976,017
+3% +$1.45M ﹤0.01% 2239
2024
Q2
$35.3M Sell
28,242,133
-1,259,098
-4% -$1.63M ﹤0.01% 2288
2024
Q1
$35.4M Sell
29,501,231
-10,250,062
-26% -$10.3M ﹤0.01% 2320
2023
Q4
$60M Buy
39,751,293
+428,520
+1% +$619K ﹤0.01% 2110
2023
Q3
$62.9M Buy
39,322,773
+11,989
+0% +$21.8K ﹤0.01% 2025
2023
Q2
$85.3M Sell
39,310,784
-2,244,148
-5% -$3.51M ﹤0.01% 1938
2023
Q1
$60.7M Buy
41,554,932
+434,438
+1% +$559K ﹤0.01% 2084
2022
Q4
$51.4M Buy
41,120,494
+835,721
+2% +$1.32M ﹤0.01% 2174
2022
Q3
$76.1M Sell
40,284,773
-2,296,471
-5% -$5.43M ﹤0.01% 1960
2022
Q2
$108M Buy
42,581,244
+6,509,113
+18% +$19M ﹤0.01% 1774
2022
Q1
$124M Buy
36,072,131
+346,707
+1% +$1.22M ﹤0.01% 1825
2021
Q4
$172M Buy
35,725,424
+259,540
+0.7% +$1.05M ﹤0.01% 1697
2021
Q3
$129M Sell
35,465,884
-266,596
-0.7% -$992K ﹤0.01% 1840
2021
Q2
$145M Buy
35,732,480
+247,389
+0.7% +$970K ﹤0.01% 1805
2021
Q1
$152M Buy
35,485,091
+1,034,937
+3% +$4.94M ﹤0.01% 1725
2020
Q4
$136M Sell
34,450,154
-1,408,746
-4% -$5.88M ﹤0.01% 1672
2020
Q3
$132M Sell
35,858,900
-1,365,860
-4% -$5.77M ﹤0.01% 1535
2020
Q2
$127M Sell
37,224,760
-147,062
-0.4% -$329K ﹤0.01% 1554
2020
Q1
$50.1M Sell
37,371,822
-172,828
-0.5% -$271K ﹤0.01% 1868
2019
Q4
$55.2M Buy
37,544,650
+3,862,958
+11% +$6.47M ﹤0.01% 2060
2019
Q3
$70.4M Buy
33,681,692
+3,214,149
+11% +$6.57M ﹤0.01% 1914
2019
Q2
$74.3M Buy
30,467,543
+812,237
+3% +$1.77M ﹤0.01% 1902
2019
Q1
$77.4M Buy
29,655,306
+1,273,653
+4% +$3.86M ﹤0.01% 1869
2018
Q4
$85.4M Sell
28,381,653
-1,279,097
-4% -$4.34M ﹤0.01% 1769
2018
Q3
$103M Buy
29,660,750
+614,442
+2% +$3.26M ﹤0.01% 1791
2018
Q2
$137M Buy
29,046,308
+1,207,884
+4% +$4.58M 0.01% 1609
2018
Q1
$88.2M Buy
27,838,424
+164,289
+0.6% +$662K ﹤0.01% 1782
2017
Q4
$136M Buy
27,674,135
+531,373
+2% +$3.08M 0.01% 1550
2017
Q3
$186M Buy
27,142,762
+524,004
+2% +$3.3M 0.01% 1317
2017
Q2
$175M Buy
26,618,758
+296,757
+1% +$2.08M 0.01% 1311
2017
Q1
$211M Buy
26,322,001
+1,112,843
+4% +$9.37M 0.01% 1189
2016
Q4
$234M Buy
25,209,158
+701,143
+3% +$7.25M 0.01% 1072
2016
Q3
$260M Buy
24,508,015
+1,406,538
+6% +$14M 0.02% 940
2016
Q2
$216M Buy
23,101,477
+161,981
+0.7% +$1.64M 0.01% 1006
2016
Q1
$238M Buy
22,939,496
+1,033,398
+5% +$9.44M 0.02% 929
2015
Q4
$220M Buy
21,906,098
+619,997
+3% +$6.21M 0.01% 950
2015
Q3
$179M Buy
21,286,101
+6,127,748
+40% +$81.1M 0.01% 1061
2015
Q2
$244M Buy
15,158,353
+1,200,954
+9% +$18.7M 0.02% 935
2015
Q1
$198M Sell
13,957,399
-481,586
-3% -$6.27M 0.01% 1052
2014
Q4
$144M Buy
14,438,985
+1,594,051
+12% +$13.6M 0.01% 1172
2014
Q3
$109M Buy
12,844,934
+171,624
+1% +$1.51M 0.01% 1286
2014
Q2
$112M Sell
12,673,310
-46,927
-0.4% -$410K 0.01% 1319
2014
Q1
$119M Buy
12,720,237
+549,210
+5% +$4.81M 0.01% 1238
2013
Q4
$103M Buy
12,171,027
+626,135
+5% +$6.33M 0.01% 1300
2013
Q3
$102M Buy
11,544,892
+3,247,748
+39% +$26.1M 0.01% 1230
2013
Q2
$58.9M Buy
+8,297,144
New +$57.3M 0.01% 1518

Other funds holding OPK

Vanguard Group's OPK Position: Q4 2025 in Review

Vanguard Group reduced its Opko Health (OPK) stake by 14% in Q4 2025, selling an estimated $7.07M and leaving 32,457,788 shares worth $40.9M. The position accounts for ﹤0.01% of the portfolio, ranked #2276.

Vanguard Group first reported a position in OPK in Q2 2013 and has held it in 51 quarters since. The position peaked at $260M in Q3 2016. 220 funds tracked by Wall St. Rank hold OPK as of Q4 2025.

  • Vanguard Group held 32,457,788 shares of Opko Health worth $40.9M as of Q4 2025.
  • Vanguard Group sold 5,078,109 Opko Health shares in Q4 2025, an estimated $7.07M.
  • Opko Health made up ﹤0.01% of Vanguard Group's portfolio in Q4 2025, its #2276 holding.
  • Vanguard Group first reported a position in Opko Health in Q2 2013 and has held it in 51 quarters since.
  • Vanguard Group's Opko Health position peaked at $260M in Q3 2016.
  • 220 funds tracked by Wall St. Rank held Opko Health as of Q4 2025.

Based on Vanguard Group's 13F filing for Q4 2025, filed 29 Jan 2026.