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Opko Health

255 hedge funds and large institutions have $401M invested in Opko Health in 2025 Q1 according to their latest regulatory filings, with 43 funds opening new positions, 76 increasing their positions, 58 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

490% more call options, than puts

Call options by funds: $5.13M | Put options by funds: $870K

87% more first-time investments, than exits

New positions opened: 43 | Existing positions closed: 23

38% more capital invested

Capital invested by funds: $290M → $401M (+$111M)

31% more repeat investments, than reductions

Existing positions increased: 76 | Existing positions reduced: 58

9% more funds holding

Funds holding: 235255 (+20)

7.1% more ownership

Funds ownership: 28.95%36.05% (+7.1%)

Holders
255
Holders Change
+20
Holders Change %
+8.51%
% of All Funds
3.42%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
43
Increased
76
Reduced
58
Closed
23
Calls
$5.13M
Puts
$870K
Net Calls
+$4.26M
Net Calls Change
+$12.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Barclays
51
Barclays
United Kingdom
$651K -$864K -524,377 -57%
SG Americas Securities
52
SG Americas Securities
New York
$585K +$580K +352,276 New
Legal & General Group
53
Legal & General Group
United Kingdom
$581K -$33.5K -20,340 -5%
ETC
54
Exchange Traded Concepts
Oklahoma
$563K -$21.3K -12,948 -4%
California State Teachers Retirement System (CalSTRS)
55
California State Teachers Retirement System (CalSTRS)
California
$538K
Verition Fund Management
56
Verition Fund Management
Connecticut
$528K +$524K +317,946 New
XT
57
XTX Topco
Cayman Islands
$513K +$189K +114,486 +59%
Squarepoint
58
Squarepoint
New York
$501K +$274K +166,523 +123%
Deutsche Bank
59
Deutsche Bank
Germany
$468K -$46.5K -28,220 -9%
Citigroup
60
Citigroup
New York
$438K -$10.2K -6,213 -2%
Tudor Investment Corp
61
Tudor Investment Corp
Connecticut
$406K
Royal Bank of Canada
62
Royal Bank of Canada
Ontario, Canada
$393K -$8.76K -5,319 -2%
Wells Fargo
63
Wells Fargo
California
$382K +$1.24K +753 +0.3%
EGM
64
Engineers Gate Manager
New York
$359K -$326K -198,096 -48%
Janus Henderson Group
65
Janus Henderson Group
United Kingdom
$352K
QT
66
Quantbot Technologies
New York
$349K +$346K +210,079 New
ECM
67
ExodusPoint Capital Management
New York
$347K +$58.6K +35,600 +20%
ZA
68
Zazove Associates
Nevada
$345K +$334K +202,700 +4,137%
IIM
69
INTECH Investment Management
Florida
$339K +$4.68K +2,839 +1%
Connor, Clark & Lunn Investment Management (CC&L)
70
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$334K +$295K +179,045 +803%
Mirae Asset Global ETFs Holdings
71
Mirae Asset Global ETFs Holdings
Hong Kong
$314K +$3.97K +2,411 +1%
IC
72
IEQ Capital
California
$304K +$244K +147,944 +418%
CM
73
Capula Management
Cayman Islands
$303K +$301K +182,512 New
State Board of Administration of Florida Retirement System
74
State Board of Administration of Florida Retirement System
Florida
$293K
GI
75
GAMCO Investors
Connecticut
$291K

OPK Hedge Fund Activity: Q1 2025 in Review

255 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Opko Health (OPK) for Q1 2025, worth a combined $401M — up 38% from $290M a quarter earlier.

Buyers outnumbered sellers: 43 funds opened new OPK positions and 23 closed out — a net gain of 20 holders — while 76 added to existing stakes and 58 trimmed.

The largest buyer was Sculptor Capital, opening a new position worth an estimated $20.9M. The largest seller was UBS Group, cutting an estimated $3.96M.

  • 255 institutional investors held Opko Health (OPK) as of Q1 2025, up from 235 in Q4 2024.
  • Funds reported $401M of Opko Health stock for Q1 2025, up 38% quarter-over-quarter.
  • 43 funds opened new Opko Health positions in Q1 2025 and 23 closed out, a net change of +20 holders.
  • The largest Opko Health buyer in Q1 2025 was Sculptor Capital, an estimated $20.9M added.
  • The largest Opko Health seller in Q1 2025 was UBS Group, an estimated $3.96M sold.

Based on aggregated 13F filings for Q1 2025.