Squarepoint’s Opko Health OPK Stock Holding History

Squarepoint’s Portfolio OPK Stock Details OPK Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q4	–	Sell	-42,519	Closed	-$59.2K	–	4710
2025 Q3	$65.9K	Sell	42,519 -49,915	-54%	-$68.6K	﹤0.01%	4186
2025 Q2	$122K	Sell	92,434 -209,427	-69%	-$286K	﹤0.01%	4118
2025 Q1	$501K	Buy	301,861 +166,523	+123%	+$274K	﹤0.01%	3301
2024 Q4	$199K	Sell	135,338 -180,692	-57%	-$276K	﹤0.01%	4477
2024 Q3	$471K	Sell	316,030 -157,186	-33%	-$233K	﹤0.01%	3140
2024 Q2	$592K	Buy	+473,216	New	+$614K	﹤0.01%	2955
2023 Q4	–	Sell	-41,810	Closed	-$66.9K	–	4354
2023 Q3	$66.9K	Buy	41,810 +21,735	+108%	+$39.6K	﹤0.01%	3609
2023 Q2	$43.6K	Sell	20,075 -17,443	-46%	-$27.3K	﹤0.01%	3451
2023 Q1	$54.8K	Sell	37,518 -20,147	-35%	-$25.9K	﹤0.01%	3045
2022 Q4	$72.1K	Sell	57,665 -7,109	-11%	-$11.2K	﹤0.01%	3007
2022 Q3	$122K	Sell	64,774 -78,937	-55%	-$187K	﹤0.01%	2771
2022 Q2	$364K	Buy	143,711 +105,786	+279%	+$308K	﹤0.01%	2177
2022 Q1	$130K	Sell	37,925 -172,778	-82%	-$610K	﹤0.01%	2565
2021 Q4	$1.01M	Buy	+210,703	New	+$853K	﹤0.01%	1681
2021 Q3	–	Sell	-191,012	Closed	-$774K	–	3279
2021 Q2	$774K	Sell	191,012 -520	-0.3%	-$2.04K	﹤0.01%	1824
2021 Q1	$822K	Sell	191,532 -54,570	-22%	-$261K	﹤0.01%	1661
2020 Q4	$972K	Sell	246,102 -719,543	-75%	-$3M	0.01%	1357
2020 Q3	$3.56M	Buy	965,645 +641,405	+198%	+$2.71M	0.05%	446
2020 Q2	$1.11M	Buy	+324,240	New	+$726K	0.02%	889
2020 Q1	–	Sell	-130,000	Closed	-$191K	–	2332
2019 Q4	$191K	Buy	130,000 +7,467	+6%	+$12.5K	﹤0.01%	2238
2019 Q3	$256K	Buy	+122,533	New	+$250K	﹤0.01%	1976
2019 Q2	–	Sell	-300,446	Closed	-$784K	–	2592
2019 Q1	$784K	Buy	300,446 +166,785	+125%	+$505K	0.01%	1222
2018 Q4	$402K	Buy	+133,661	New	+$453K	﹤0.01%	1371
2018 Q3	–	Sell	-161,511	Closed	-$759K	–	2153
2018 Q2	$759K	Buy	161,511 +96,385	+148%	+$366K	0.01%	1002
2018 Q1	$206K	Buy	+65,126	New	+$262K	﹤0.01%	1479
2017 Q4	–	Sell	-18,937	Closed	-$130K	–	2276
2017 Q3	$130K	Sell	18,937 -146,422	-89%	-$923K	﹤0.01%	1480
2017 Q2	$1.09M	Buy	165,359 +139,980	+552%	+$981K	0.02%	700
2017 Q1	$203K	Buy	25,379 +14,666	+137%	+$123K	0.01%	1281
2016 Q4	$100K	Sell	10,713 -1,287	-11%	-$13.3K	﹤0.01%	1624
2016 Q3	$127K	Sell	12,000 -31,000	-72%	-$309K	0.01%	937
2016 Q2	$402K	Buy	+43,000	New	+$437K	0.03%	624
2016 Q1	–	Sell	-110,200	Closed	-$1.11M	–	1374
2015 Q4	$1.11M	Buy	110,200 +50,700	+85%	+$508K	0.12%	238
2015 Q3	$500K	Buy	+59,500	New	+$788K	0.12%	195
2015 Q2	–	Sell	-20,200	Closed	-$286K	–	566
2015 Q1	$286K	Buy	+20,200	New	+$263K	0.1%	300

Other funds holding OPK

RCMNY

Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return

UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return

WCM

Whitefort Capital Management New York $339M AUM 52.48% 1-Year Est. Return

Northern Trust Chicago, Illinois $757B AUM 28.64% 1-Year Est. Return

Squarepoint's OPK Position: Q4 2025 in Review

Squarepoint sold out of Opko Health (OPK) in Q4 2025, closing a stake of 42,519 shares — an estimated $59.2K sold.

Squarepoint first reported a position in OPK in Q1 2015 and held it in 34 quarters. The position peaked at $3.56M in Q3 2020. 220 funds tracked by Wall St. Rank hold OPK as of Q4 2025.

Squarepoint reported no remaining Opko Health position as of Q4 2025 after selling out during the quarter.
Squarepoint sold 42,519 Opko Health shares in Q4 2025, an estimated $59.2K.
Squarepoint first reported a position in Opko Health in Q1 2015 and held it in 34 quarters.
Squarepoint's Opko Health position peaked at $3.56M in Q3 2020.
220 funds tracked by Wall St. Rank held Opko Health as of Q4 2025.

Based on Squarepoint's 13F filing for Q4 2025, filed 13 Feb 2026.