|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$256M
|
+$250K
|
+8,426
|
+0.1%
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$198M
|
+$53.1M
|
+1,791,462
|
+45%
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$170M
|
+$77M
|
+2,598,561
|
+109%
|
|
|
4
|
|
$120M
|
+$7.24M
|
+244,240
|
+7%
|
|
|
5
|
|
$86.1M
|
+$9.27M
|
+312,810
|
+14%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$75.5M
|
-$1.34M
|
-45,246
|
-2%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$75.2M
|
-$9.37M
|
-316,399
|
-13%
|
|
|
8
|
Woodline Partners
San Francisco,
California
|
$60.8M
|
+$49.9M
|
+1,683,202
|
+1,683%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$55.8M
|
-$30.4M
|
-1,027,402
|
-39%
|
|
|
10
|
Point72 Asset Management
Stamford,
Connecticut
|
$49.8M
|
-$95.6M
|
-3,225,798
|
-69%
|
|
|
11
|
Pictet Asset Management
Carouge,
Switzerland
|
$34.7M
|
-$5.01M
|
-168,996
|
-14%
|
|
|
12
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$33.9M
|
–
|
–
|
–
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$33.1M
|
+$2.22M
|
+74,786
|
+8%
|
|
|
14
|
|
$21.6M
|
+$2.66M
|
+89,628
|
+16%
|
|
|
15
|
|
$20.9M
|
+$1.6M
|
+54,000
|
+10%
|
|
|
16
|
Silverarc Capital Management
Boston,
Massachusetts
|
$16.6M
|
+$69.1K
|
+2,334
|
+0.5%
|
|
|
17
|
Two Sigma Advisers
New York
|
$13.6M
|
+$459K
|
+15,500
|
+4%
|
|
|
18
|
Novo Holdings A/S
Hellerup,
Denmark
|
$12.8M
|
+$11.1M
|
+375,000
|
New
|
|
|
19
|
MPM BioImpact
Boston,
Massachusetts
|
$12.6M
|
+$1.3M
|
+44,051
|
+14%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$11.6M
|
+$13.6K
|
+460
|
+0.1%
|
|
|
21
|
Charles Schwab
San Francisco,
California
|
$11.2M
|
+$34K
|
+1,147
|
+0.4%
|
|
|
22
|
Affinity Asset Advisors
New York
|
$8.54M
|
+$758K
|
+25,573
|
+11%
|
|
|
23
|
DAFNA Capital Management
Los Angeles,
California
|
$7.9M
|
–
|
–
|
–
|
|
|
24
|
Fiduciary Trust
Boston,
Massachusetts
|
$7.3M
|
–
|
–
|
–
|
|
|
25
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$7.3M
|
-$1.06M
|
-35,779
|
-14%
|
|
