|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$223M
|
+$896K
|
+21,401
|
+0.4%
|
|
|
2
|
EcoR1 Capital
San Francisco,
California
|
$159M
|
–
|
–
|
–
|
|
|
3
|
|
$73M
|
+$679K
|
+16,226
|
+0.9%
|
|
|
4
|
|
$66.2M
|
+$2.72M
|
+64,951
|
+4%
|
|
|
5
|
Novo Holdings A/S
Hellerup,
Denmark
|
$65.6M
|
-$17.4M
|
-415,635
|
-20%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$49.7M
|
+$1.72M
|
+41,094
|
+3%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$48.2M
|
+$9.53M
|
+227,635
|
+23%
|
|
|
8
|
Omega Fund Management
Boston,
Massachusetts
|
$48.2M
|
–
|
–
|
–
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$44.7M
|
-$1.41M
|
-33,710
|
-3%
|
|
|
10
|
Holocene Advisors
New York
|
$31.4M
|
+$18.7M
|
+447,177
|
+134%
|
|
|
11
|
Perceptive Advisors
New York
|
$30.8M
|
-$2.9M
|
-69,194
|
-8%
|
|
|
12
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$25.3M
|
+$13.3M
|
+318,839
|
+102%
|
|
|
13
|
Point72 Asset Management
Stamford,
Connecticut
|
$24.8M
|
+$6.74M
|
+160,934
|
+35%
|
|
|
14
|
Marshall Wace
London,
United Kingdom
|
$24.1M
|
-$2.55M
|
-60,873
|
-9%
|
|
|
15
|
Affinity Asset Advisors
New York
|
$18.7M
|
+$2.78M
|
+66,352
|
+17%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$17.8M
|
-$24.2K
|
-579
|
-0.1%
|
|
|
17
|
Wellington Management Group
Boston,
Massachusetts
|
$16.9M
|
+$17.7M
|
+422,146
|
New
|
|
|
18
|
Driehaus Capital Management
Chicago,
Illinois
|
$15.4M
|
-$5.56M
|
-132,956
|
-26%
|
|
|
19
|
Dimensional Fund Advisors
Austin,
Texas
|
$14.7M
|
+$2.43M
|
+58,015
|
+19%
|
|
|
20
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
$13.3M
|
-$872K
|
-20,843
|
-6%
|
|
|
21
|
Polar Capital Holdings
London,
United Kingdom
|
$13M
|
–
|
–
|
–
|
|
|
22
|
RA Capital Management
Boston,
Massachusetts
|
$11.2M
|
+$11.7M
|
+278,874
|
New
|
|
|
23
|
|
$8.83M
|
+$4.45M
|
+106,424
|
+94%
|
|
|
24
|
Fiduciary Trust
Boston,
Massachusetts
|
$8.61M
|
–
|
–
|
–
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$8.54M
|
-$714K
|
-17,070
|
-7%
|
|
