|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$263M
|
+$4.11M
|
+76,572
|
+1%
|
|
|
2
|
EcoR1 Capital
San Francisco,
California
|
$187M
|
–
|
–
|
–
|
|
|
3
|
Novo Holdings A/S
Hellerup,
Denmark
|
$97.2M
|
–
|
–
|
–
|
|
|
4
|
|
$85.4M
|
+$11.4M
|
+213,051
|
+13%
|
|
|
5
|
|
$75.1M
|
–
|
–
|
–
|
|
|
6
|
Omega Fund Management
Boston,
Massachusetts
|
$56.9M
|
-$6.22M
|
-115,938
|
-9%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$56.7M
|
+$552K
|
+10,289
|
+0.9%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$54.3M
|
+$6.76M
|
+126,142
|
+12%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$46.1M
|
+$3.46M
|
+64,447
|
+7%
|
|
|
10
|
Perceptive Advisors
New York
|
$39.6M
|
-$2.73M
|
-50,819
|
-6%
|
|
|
11
|
Marshall Wace
London,
United Kingdom
|
$31.3M
|
+$34.4M
|
+640,847
|
+3,349%
|
|
|
12
|
Driehaus Capital Management
Chicago,
Illinois
|
$24.5M
|
+$2.89M
|
+53,802
|
+12%
|
|
|
13
|
Point72 Asset Management
Stamford,
Connecticut
|
$21.6M
|
+$8.31M
|
+155,015
|
+51%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$21M
|
+$754K
|
+14,051
|
+3%
|
|
|
15
|
Affinity Asset Advisors
New York
|
$18.9M
|
+$6.89M
|
+128,547
|
+47%
|
|
|
16
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
$16.6M
|
-$1.59M
|
-29,577
|
-8%
|
|
|
17
|
Holocene Advisors
New York
|
$15.9M
|
+$4.02M
|
+75,031
|
+29%
|
|
|
18
|
Polar Capital Holdings
London,
United Kingdom
|
$15.4M
|
+$4.02M
|
+75,000
|
+30%
|
|
|
19
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$14.8M
|
-$624K
|
-11,636
|
-4%
|
|
|
20
|
Dimensional Fund Advisors
Austin,
Texas
|
$14.6M
|
+$3.82M
|
+71,138
|
+30%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$10.9M
|
+$150K
|
+2,802
|
+1%
|
|
|
22
|
Fiduciary Trust
Boston,
Massachusetts
|
$10.2M
|
–
|
–
|
–
|
|
|
23
|
DAFNA Capital Management
Los Angeles,
California
|
$8.6M
|
–
|
–
|
–
|
|
|
24
|
|
$8.58M
|
+$521K
|
+9,721
|
+6%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$8.27M
|
+$335K
|
+6,240
|
+4%
|
|
