|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$312M
|
+$2.19M
|
+39,742
|
+0.7%
|
|
|
2
|
EcoR1 Capital
San Francisco,
California
|
$227M
|
+$52.4M
|
+952,251
|
+32%
|
|
|
3
|
Novo Holdings A/S
Hellerup,
Denmark
|
$152M
|
–
|
–
|
–
|
|
|
4
|
|
$104M
|
–
|
–
|
–
|
|
|
5
|
Omega Fund Management
Boston,
Massachusetts
|
$101M
|
-$27.8M
|
-505,128
|
-22%
|
|
|
6
|
|
$83.4M
|
+$16.4M
|
+297,877
|
+26%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$56M
|
+$1.44M
|
+26,261
|
+3%
|
|
|
8
|
Perceptive Advisors
New York
|
$53.8M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$49.5M
|
+$34.1M
|
+620,326
|
+257%
|
|
|
10
|
Marshall Wace North America
New York
|
$33.3M
|
-$226K
|
-4,105
|
-0.7%
|
|
|
11
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
$24.3M
|
+$1.56M
|
+28,375
|
+7%
|
|
|
12
|
Driehaus Capital Management
Chicago,
Illinois
|
$23.7M
|
+$11.5M
|
+208,352
|
+102%
|
|
|
13
|
Alkeon Capital Management
New York
|
$22.5M
|
–
|
–
|
–
|
|
|
14
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$21.4M
|
+$156K
|
+2,844
|
+0.8%
|
|
|
15
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$18.5M
|
+$1.22M
|
+22,170
|
+7%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$18M
|
+$3.61M
|
+65,571
|
+27%
|
|
|
17
|
Rubric Capital Management (New York)
New York
|
$17.5M
|
+$11.8M
|
+215,363
|
+242%
|
|
|
18
|
Point72 Asset Management
Stamford,
Connecticut
|
$15.9M
|
-$7.51M
|
-136,500
|
-33%
|
|
|
19
|
Affinity Asset Advisors
New York
|
$14.1M
|
+$2.82M
|
+51,201
|
+26%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$12.5M
|
+$2.24M
|
+40,717
|
+23%
|
|
|
21
|
Cormorant Asset Management
Boston,
Massachusetts
|
$10.9M
|
-$8.82M
|
-160,226
|
-46%
|
|
|
22
|
DAFNA Capital Management
Los Angeles,
California
|
$10.4M
|
–
|
–
|
–
|
|
|
23
|
Polar Capital Holdings
London,
United Kingdom
|
$8.61M
|
–
|
–
|
–
|
|
|
24
|
Dimensional Fund Advisors
Austin,
Texas
|
$6.92M
|
+$6.63M
|
+120,482
|
New
|
|
|
25
|
Nuveen
Charlotte,
North Carolina
|
$6.9M
|
+$2.85M
|
+51,844
|
+76%
|
|
