We are live on ! Find out more
LXRX icon

Lexicon Pharmaceuticals

125 hedge funds and large institutions have $299M invested in Lexicon Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 23 funds opening new positions, 28 increasing their positions, 41 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed

292% more call options, than puts

Call options by funds: $1.13M | Put options by funds: $289K

35% more first-time investments, than exits

New positions opened: 23 | Existing positions closed: 17

2% more funds holding

Funds holding: 123125 (+2)

1.46% more ownership

Funds ownership: 70.21%71.66% (+1.5%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

13% less capital invested

Capital invested by funds: $344M → $299M (-$44.9M)

32% less repeat investments, than reductions

Existing positions increased: 28 | Existing positions reduced: 41

Holders
125
Holders Change
+2
Holders Change %
+1.63%
% of All Funds
1.52%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
23
Increased
28
Reduced
41
Closed
17
Calls
$1.13M
Puts
$289K
Net Calls
+$844K
Net Calls Change
-$2.49M
Name Holding Trade Value Shares
Change
Change in
Stake
Point72 Asset Management
26
Point72 Asset Management
Connecticut
$327K +$390K +284,025 New
OAC
27
OMERS Administration Corp
Ontario, Canada
$315K +$376K +273,800 New
ECM
28
ExodusPoint Capital Management
New York
$309K +$369K +268,433 New
Renaissance Technologies
29
Renaissance Technologies
New York
$303K -$40K -29,146 -10%
Group One Trading
30
Group One Trading
Illinois
$258K +$11.1K +8,064 +4%
Barclays
31
Barclays
United Kingdom
$224K +$224K +162,881 +511%
Morgan Stanley
32
Morgan Stanley
New York
$222K +$33K +24,017 +14%
Two Sigma Advisers
33
Two Sigma Advisers
New York
$208K +$249K +180,977 New
IC
34
Ikarian Capital
Texas
$189K -$16.2K -11,805 -7%
Cerity Partners
35
Cerity Partners
New York
$167K -$18K -13,096 -8%
AQR Capital Management
36
AQR Capital Management
Connecticut
$167K -$217K -158,131 -52%
HT
37
Headlands Technologies
Illinois
$157K +$119K +86,466 +174%
LIP
38
Lighthouse Investment Partners
Florida
$146K +$174K +126,600 New
HF
39
HRT Financial
New York
$135K +$97.7K +71,102 +153%
MAM
40
Monaco Asset Management
Monaco
$135K -$320K -232,812 -67%
TSS
41
Two Sigma Securities
New York
$132K +$136K +98,751 +622%
GCM
42
Graham Capital Management
Connecticut
$126K +$151K +109,900 New
Bank of America
43
Bank of America
North Carolina
$117K +$60.8K +44,293 +77%
Hudson Bay Capital Management
44
Hudson Bay Capital Management
Connecticut
$116K +$138K +100,532 New
XT
45
XTX Topco
Cayman Islands
$111K -$321K -233,446 -71%
JFG
46
Jefferies Financial Group
New York
$106K -$6.69K -4,870 -5%
Citigroup
47
Citigroup
New York
$105K +$101K +73,551 +406%
QL
48
Quarry LP
New York
$101K +$121K +88,000 New
LPL Financial
49
LPL Financial
California
$100K -$5.77K -4,201 -5%
CAU
50
Caxton Associates (UK)
$81.7K +$97.6K +71,027 New