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Two Sigma Securities’s Lexicon Pharmaceuticals LXRX Stock Holding History

Two Sigma Securities’s Portfolio LXRX Stock Details LXRX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$159K Buy
+66,375
New +$129K 0.01% 1215
2026
Q1 		– Sell
-114,632
Closed -$132K – 1966
2025
Q4 		$132K Buy
114,632
+98,751
+622% +$136K 0.02% 936
2025
Q3 		$21.4K Sell
15,881
-26,524
-63% -$30.1K ﹤0.01% 1129
2025
Q2 		$40.1K Buy
+42,405
New +$27.5K ﹤0.01% 1129
2024
Q4 		– Sell
-24,527
Closed -$38.5K – 2548
2024
Q3 		$38.5K Buy
24,527
+6,756
+38% +$12K ﹤0.01% 2401
2024
Q2 		$29.9K Buy
+17,771
New +$31.9K ﹤0.01% 2639
2024
Q1 		– Sell
-38,268
Closed -$58.5K – 3337
2023
Q4 		$58.5K Buy
+38,268
New +$45.5K ﹤0.01% 2584
2021
Q1 		– Sell
-20,003
Closed -$68K – 1374
2020
Q4 		$68K Buy
+20,003
New +$38.2K ﹤0.01% 1539

Other funds holding LXRX

AG
Artal Group Luxembourg $931M AUM 41.63% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
SC
Sessa Capital New York $5.98B AUM 99.85% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Point72 Asset Management
Point72 Asset Management Stamford, Connecticut $90.7B AUM 77.13% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

Two Sigma Securities's LXRX Position: Q2 2026 in Review

Two Sigma Securities opened a new position in Lexicon Pharmaceuticals (LXRX) in Q2 2026: 66,375 shares worth $159K. The stake represents 0.01% of the portfolio and ranks #1215 among its holdings. This is a return to the name: Two Sigma Securities previously reported a position in LXRX as recently as Q4 2025.

Two Sigma Securities first reported a position in LXRX in Q4 2020 and has held it in 8 quarters since. 149 funds tracked by Wall St. Rank hold LXRX as of Q2 2026.

  • Two Sigma Securities held 66,375 shares of Lexicon Pharmaceuticals worth $159K as of Q2 2026.
  • Lexicon Pharmaceuticals was a new Two Sigma Securities position in Q2 2026.
  • Lexicon Pharmaceuticals made up 0.01% of Two Sigma Securities's portfolio in Q2 2026, its #1215 holding.
  • Two Sigma Securities first reported a position in Lexicon Pharmaceuticals in Q4 2020 and has held it in 8 quarters since.
  • 149 funds tracked by Wall St. Rank held Lexicon Pharmaceuticals as of Q2 2026.

Based on Two Sigma Securities's 13F filing for Q2 2026, filed 14 Aug 2026.