|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$260M
|
+$2.01M
|
+63,429
|
+0.7%
|
|
|
2
|
|
$148M
|
+$9.23M
|
+291,590
|
+6%
|
|
|
3
|
Avoro Capital Advisors
New York
|
$113M
|
–
|
–
|
–
|
|
|
4
|
EcoR1 Capital
San Francisco,
California
|
$104M
|
+$60.7M
|
+1,919,600
|
+108%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$94.1M
|
+$3.02M
|
+95,476
|
+3%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$80.1M
|
+$4.95M
|
+156,430
|
+6%
|
|
|
7
|
Ameriprise
Minneapolis,
Minnesota
|
$69.9M
|
+$44.8M
|
+1,416,480
|
+134%
|
|
|
8
|
Holocene Advisors
New York
|
$63.4M
|
+$19.7M
|
+621,806
|
+38%
|
|
|
9
|
Foresite Capital Management IV
Larkspur,
California
|
$52.3M
|
+$1.33M
|
+41,965
|
+2%
|
|
|
10
|
|
$47.9M
|
+$44.7M
|
+1,412,295
|
+499%
|
|
|
11
|
Wellington Management Group
Boston,
Massachusetts
|
$47.7M
|
+$11.1M
|
+350,789
|
+26%
|
|
|
12
|
Victory Capital Management
San Antonio,
Texas
|
$47.3M
|
+$4.47M
|
+141,324
|
+9%
|
|
|
13
|
BVF Inc
San Francisco,
California
|
$46.2M
|
+$12.3M
|
+389,200
|
+31%
|
|
|
14
|
Eventide Asset Management
Boston,
Massachusetts
|
$45.7M
|
+$17.6M
|
+557,573
|
+53%
|
|
|
15
|
Citadel Advisors
Miami,
Florida
|
$40.6M
|
-$51.6M
|
-1,632,396
|
-53%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$30.7M
|
+$2.91M
|
+91,966
|
+9%
|
|
|
17
|
|
$30.6M
|
-$19.6M
|
-619,869
|
-36%
|
|
|
18
|
Boxer Capital
San Diego,
California
|
$29.7M
|
–
|
–
|
–
|
|
|
19
|
|
$29.5M
|
-$6.69M
|
-211,289
|
-17%
|
|
|
20
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$29.2M
|
-$158
|
-5
|
-0%
|
|
|
21
|
Eagle Asset Management
St Petersburg,
Florida
|
$24.8M
|
+$1.75M
|
+55,226
|
+7%
|
|
|
22
|
Dimensional Fund Advisors
Austin,
Texas
|
$23.1M
|
+$5.4M
|
+170,582
|
+26%
|
|
|
23
|
Franklin Resources
San Mateo,
California
|
$21M
|
+$7.6M
|
+240,144
|
+48%
|
|
|
24
|
Suvretta Capital Management
New York
|
$20.7M
|
+$14.6M
|
+460,915
|
+170%
|
|
|
25
|
Sphera Funds Management
Tel Aviv,
Israel
|
$20.3M
|
+$7.79M
|
+246,257
|
+52%
|
|
