|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$83.1M
|
+$45.8M
|
+2,352,344
|
+113%
|
|
|
2
|
EcoR1 Capital
San Francisco,
California
|
$70.6M
|
–
|
–
|
–
|
|
|
3
|
Great Point Partners
Greenwich,
Connecticut
|
$44.6M
|
+$3.57M
|
+183,563
|
+8%
|
|
|
4
|
|
$29.9M
|
+$1.37M
|
+70,485
|
+5%
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$25.4M
|
–
|
–
|
–
|
|
|
6
|
PFM Health Sciences
San Francisco,
California
|
$25.1M
|
-$8.03M
|
-412,762
|
-24%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$23.4M
|
+$3.09M
|
+158,515
|
+15%
|
|
|
8
|
Boxer Capital
San Diego,
California
|
$15.8M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$14.6M
|
+$9.55M
|
+490,758
|
+170%
|
|
|
10
|
Sio Capital Management
New York
|
$12.3M
|
+$5.17M
|
+265,384
|
+68%
|
|
|
11
|
Millennium Management
New York
|
$9.79M
|
+$4.25M
|
+218,306
|
+72%
|
|
|
12
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$7.22M
|
-$2.53M
|
-130,000
|
-25%
|
|
|
13
|
Nexthera Capital
New York
|
$6.6M
|
-$1.82M
|
-93,595
|
-21%
|
|
|
14
|
Sphera Funds Management
Tel Aviv,
Israel
|
$6.19M
|
+$6.42M
|
+330,000
|
New
|
|
|
15
|
Northern Trust
Chicago,
Illinois
|
$4.79M
|
+$408K
|
+20,961
|
+9%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$4.37M
|
+$1.29M
|
+66,417
|
+40%
|
|
|
17
|
Alethea Capital Management
Mercer Island,
Washington
|
$3.39M
|
+$1.77M
|
+90,922
|
+101%
|
|
|
18
|
Clough Capital Partners
Boston,
Massachusetts
|
$3.16M
|
-$862K
|
-44,300
|
-21%
|
|
|
19
|
Tiverton Asset Management
Wilimington,
Delaware
|
$2.61M
|
+$2.71M
|
+138,964
|
New
|
|
|
20
|
DAFNA Capital Management
Los Angeles,
California
|
$2.38M
|
+$189K
|
+9,719
|
+8%
|
|
|
21
|
Minerva Advisors
Bala Cynwyd,
Pennsylvania
|
$1.93M
|
-$1.32M
|
-67,900
|
-40%
|
|
|
22
|
|
$1.88M
|
–
|
–
|
–
|
|
|
23
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$1.86M
|
+$892K
|
+45,813
|
+85%
|
|
|
24
|
|
$1.76M
|
+$1.83M
|
+94,132
|
New
|
|
|
25
|
Schonfeld Strategic Advisors
New York
|
$1.6M
|
+$1.67M
|
+85,576
|
New
|
|
