|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$303M
|
-$150K
|
-13,100
|
-0.1%
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$265M
|
+$5.03M
|
+439,296
|
+2%
|
|
|
3
|
Janus Henderson Investors US
Denver,
Colorado
|
$219M
|
+$16.9M
|
+1,472,297
|
+9%
|
|
|
4
|
|
$184M
|
–
|
–
|
–
|
|
|
5
|
|
$118M
|
-$4.48M
|
-391,042
|
-4%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$116M
|
+$3.11M
|
+271,671
|
+3%
|
|
|
7
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$108M
|
+$22.6M
|
+1,978,688
|
+31%
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$81.8M
|
+$7.62M
|
+665,708
|
+12%
|
|
|
9
|
BVF Inc
San Francisco,
California
|
$78M
|
-$6.88M
|
-600,887
|
-9%
|
|
|
10
|
State of Wisconsin Investment Board
Madison,
Wisconsin
|
$57.1M
|
-$15.6M
|
-1,367,144
|
-23%
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
$49.3M
|
+$349K
|
+30,503
|
+0.8%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$45.4M
|
-$416K
|
-36,329
|
-1%
|
|
|
13
|
Millennium Management
New York
|
$40.9M
|
+$18.2M
|
+1,588,435
|
+99%
|
|
|
14
|
Fred Alger Management
New York
|
$28.8M
|
+$3.5M
|
+305,514
|
+16%
|
|
|
15
|
Capital World Investors
Los Angeles,
California
|
$24.6M
|
–
|
–
|
–
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$24.5M
|
-$891K
|
-77,847
|
-4%
|
|
|
17
|
Point72 Asset Management
Stamford,
Connecticut
|
$23M
|
+$2.84M
|
+247,874
|
+16%
|
|
|
18
|
Sector Gamma AS
Oslo,
Norway
|
$17.5M
|
+$94.3K
|
+8,239
|
+0.6%
|
|
|
19
|
Asset Management One
Tokyo,
Japan
|
$17.3M
|
+$3.65M
|
+318,738
|
+30%
|
|
|
20
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$14.9M
|
-$6.1M
|
-532,621
|
-31%
|
|
|
21
|
EcoR1 Capital
San Francisco,
California
|
$13.8M
|
+$12.3M
|
+1,074,600
|
New
|
|
|
22
|
Senzar Asset Management
New York
|
$12M
|
+$10.7M
|
+933,469
|
New
|
|
|
23
|
Tekla Capital Management
Boston,
Massachusetts
|
$11.8M
|
–
|
–
|
–
|
|
|
24
|
|
$11.6M
|
+$5.07M
|
+442,602
|
+96%
|
|
|
25
|
|
$11M
|
+$2.53M
|
+220,932
|
+35%
|
|
