|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$256M
|
–
|
–
|
–
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$219M
|
+$2.65M
|
+231,458
|
+1%
|
|
|
3
|
Janus Henderson Investors US
Denver,
Colorado
|
$169M
|
+$92.6M
|
+8,088,817
|
+108%
|
|
|
4
|
|
$156M
|
+$42M
|
+3,672,982
|
+34%
|
|
|
5
|
|
$104M
|
-$408K
|
-35,644
|
-0.4%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$94.8M
|
+$1.58M
|
+137,801
|
+2%
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$72.5M
|
-$49.4M
|
-4,312,541
|
-39%
|
|
|
8
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$69.4M
|
+$19.9M
|
+1,738,952
|
+37%
|
|
|
9
|
State of Wisconsin Investment Board
Madison,
Wisconsin
|
$63.1M
|
+$1.61M
|
+140,892
|
+2%
|
|
|
10
|
BlackRock Fund Advisors
San Francisco,
California
|
$61.9M
|
+$798K
|
+69,671
|
+1%
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
$41.4M
|
-$1.03M
|
-89,550
|
-2%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$38.8M
|
+$2.92M
|
+254,677
|
+8%
|
|
|
13
|
Northern Trust
Chicago,
Illinois
|
$21.5M
|
+$4.94M
|
+431,924
|
+28%
|
|
|
14
|
Fred Alger Management
New York
|
$21.1M
|
+$6.75M
|
+589,304
|
+44%
|
|
|
15
|
Capital World Investors
Los Angeles,
California
|
$20.8M
|
–
|
–
|
–
|
|
|
16
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$18.4M
|
-$410K
|
-35,820
|
-2%
|
|
|
17
|
Millennium Management
New York
|
$17.3M
|
-$27.8M
|
-2,424,438
|
-60%
|
|
|
18
|
Point72 Asset Management
Stamford,
Connecticut
|
$16.7M
|
+$17.7M
|
+1,543,245
|
New
|
|
|
19
|
Sector Gamma AS
Oslo,
Norway
|
$14.7M
|
-$276K
|
-24,119
|
-2%
|
|
|
20
|
Asset Management One
Tokyo,
Japan
|
$11.9M
|
+$12.2M
|
+1,065,114
|
New
|
|
|
21
|
Fidelity International
Hamilton,
Bermuda
|
$10.7M
|
–
|
–
|
–
|
|
|
22
|
Tekla Capital Management
Boston,
Massachusetts
|
$10M
|
–
|
–
|
–
|
|
|
23
|
|
$9.3M
|
+$96.5K
|
+8,432
|
+1%
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$9.05M
|
+$93.9K
|
+8,199
|
+1%
|
|
|
25
|
Clough Capital Partners
Boston,
Massachusetts
|
$8.17M
|
-$10.1M
|
-885,351
|
-54%
|
|
