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Ironwood Pharmaceuticals
IRWD

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$146M +$213M +17,540,520 New
Wellington Management Group
2
Wellington Management Group
Massachusetts
$131M +$191M +15,758,634 New
Morgan Stanley
3
Morgan Stanley
New York
$96.5M +$141M +11,605,930 New
BI
4
BVF Inc
California
$52.3M +$76M +6,271,558 New
Vanguard Group
5
Vanguard Group
Pennsylvania
$51.3M +$74.6M +6,152,619 New
SAM
6
Sectoral Asset Management
Quebec, Canada
$50.5M +$73.7M +6,077,516 New
JHIU
7
Janus Henderson Investors US
Colorado
$45.7M +$66.4M +5,481,176 New
State of Wisconsin Investment Board
8
State of Wisconsin Investment Board
Wisconsin
$43.8M +$63.7M +5,253,576 New
BFA
9
BlackRock Fund Advisors
California
$33.9M +$49.4M +4,072,539 New
WRF
10
Waddell & Reed Financial
Kansas
$32.6M +$47.4M +3,907,420 New
State Street
11
State Street
Massachusetts
$29.9M +$43.4M +3,583,620 New
Capital World Investors
12
Capital World Investors
California
$29.1M +$42.3M +3,492,450 New
BIT
13
BlackRock Institutional Trust
California
$24.9M +$36.4M +2,999,260 New
CGT
14
Capital Guardian Trust
California
$23.2M +$33.7M +2,781,558 New
VM
15
VHCP Management
New York
$17.9M +$26M +2,149,200 New
Adage Capital Partners
16
Adage Capital Partners
Massachusetts
$16.8M +$24.5M +2,018,948 New
T. Rowe Price Associates
17
T. Rowe Price Associates
Maryland
$16M +$23.3M +1,924,847 New
TG
18
TCW Group
California
$15.4M +$22.4M +1,844,311 New
Northern Trust
19
Northern Trust
Illinois
$12.3M +$17.9M +1,475,782 New
OIM
20
Oracle Investment Management
Connecticut
$11M +$16M +1,321,856 New
BBA
21
Baker Bros. Advisors
New York
$9.16M +$13.3M +1,101,059 New
RNS
22
Robert N. Shapiro
$8.35M +$12.2M +1,004,051 New
Fidelity International
23
Fidelity International
Bermuda
$8.21M +$12M +987,157 New
TCM
24
Tekla Capital Management
Massachusetts
$7.64M +$11.1M +917,052 New
FIG
25
Fortress Investment Group
New York
$5.1M +$7.42M +612,383 New
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