|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$303M
|
–
|
–
|
–
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$256M
|
+$1.08M
|
+98,980
|
+0.5%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$141M
|
-$1.22M
|
-112,349
|
-1%
|
|
|
4
|
|
$137M
|
+$102M
|
+9,377,438
|
+726%
|
|
|
5
|
|
$124M
|
-$583K
|
-53,605
|
-0.6%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$110M
|
+$714K
|
+65,707
|
+0.8%
|
|
|
7
|
Janus Henderson Investors US
Denver,
Colorado
|
$96.3M
|
+$4.3M
|
+395,394
|
+6%
|
|
|
8
|
State of Wisconsin Investment Board
Madison,
Wisconsin
|
$72.9M
|
-$20.1M
|
-1,844,137
|
-25%
|
|
|
9
|
BlackRock Fund Advisors
San Francisco,
California
|
$72.4M
|
-$3.1M
|
-285,308
|
-5%
|
|
|
10
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$59.9M
|
-$31.9M
|
-2,934,646
|
-39%
|
|
|
11
|
Millennium Management
New York
|
$51.6M
|
-$25.2M
|
-2,317,149
|
-37%
|
|
|
12
|
BlackRock Institutional Trust
San Francisco,
California
|
$50.1M
|
+$1.29M
|
+118,902
|
+3%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$42.7M
|
-$4.75M
|
-436,487
|
-12%
|
|
|
14
|
Oracle Investment Management
Greenwich,
Connecticut
|
$24.8M
|
-$2.92M
|
-268,769
|
-12%
|
|
|
15
|
Capital World Investors
Los Angeles,
California
|
$24.6M
|
-$584K
|
-53,730
|
-3%
|
|
|
16
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$22.2M
|
-$5.19M
|
-477,642
|
-22%
|
|
|
17
|
Clough Capital Partners
Boston,
Massachusetts
|
$21M
|
+$5.53M
|
+508,167
|
+45%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$19.9M
|
-$5.56M
|
-511,315
|
-25%
|
|
|
19
|
Adage Capital Partners
Boston,
Massachusetts
|
$17.9M
|
+$9.48M
|
+871,658
|
+167%
|
|
|
20
|
Sector Gamma AS
Oslo,
Norway
|
$17.8M
|
+$1.71M
|
+157,011
|
+13%
|
|
|
21
|
Fred Alger Management
New York
|
$17.4M
|
-$133K
|
-12,188
|
-0.9%
|
|
|
22
|
Fidelity International
Hamilton,
Bermuda
|
$12.7M
|
–
|
–
|
–
|
|
|
23
|
Tekla Capital Management
Boston,
Massachusetts
|
$11.8M
|
–
|
–
|
–
|
|
|
24
|
Turner Investments
Berwyn,
Pennsylvania
|
$11.8M
|
-$4.66M
|
-428,789
|
-32%
|
|
|
25
|
Tamarack Capital Management
Carlsbad,
California
|
$11.5M
|
+$10.4M
|
+955,200
|
New
|
|
