|
1
|
Fidelity Investments
Boston,
Massachusetts
|
303 Mio. $
|
-149.927 $
|
-13.100
|
-0,1 %
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
265 Mio. $
|
+5,03 Mio. $
|
+439.296
|
+2 %
|
|
|
3
|
Janus Henderson Investors US
Denver,
Colorado
|
219 Mio. $
|
+16,9 Mio. $
|
+1.472.297
|
+9 %
|
|
|
4
|
|
184 Mio. $
|
–
|
–
|
–
|
|
|
5
|
|
118 Mio. $
|
-4,48 Mio. $
|
-391.042
|
-4 %
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
116 Mio. $
|
+3,11 Mio. $
|
+271.671
|
+3 %
|
|
|
7
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
108 Mio. $
|
+22,6 Mio. $
|
+1.978.688
|
+31 %
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
81,8 Mio. $
|
+7,62 Mio. $
|
+665.708
|
+12 %
|
|
|
9
|
BVF Inc
San Francisco,
California
|
78 Mio. $
|
-6,88 Mio. $
|
-600.887
|
-9 %
|
|
|
10
|
State of Wisconsin Investment Board
Madison,
Wisconsin
|
57,1 Mio. $
|
-15,6 Mio. $
|
-1.367.144
|
-23 %
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
49,3 Mio. $
|
+349.101 $
|
+30.503
|
+0,8 %
|
|
|
12
|
State Street
Boston,
Massachusetts
|
45,4 Mio. $
|
-415.778 $
|
-36.329
|
-1 %
|
|
|
13
|
Millennium Management
New York
|
40,9 Mio. $
|
+18,2 Mio. $
|
+1.588.435
|
+99 %
|
|
|
14
|
Fred Alger Management
New York
|
28,8 Mio. $
|
+3,5 Mio. $
|
+305.514
|
+16 %
|
|
|
15
|
Capital World Investors
Los Angeles,
California
|
24,6 Mio. $
|
–
|
–
|
–
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
24,5 Mio. $
|
-890.943 $
|
-77.847
|
-4 %
|
|
|
17
|
Point72 Asset Management
Stamford,
Connecticut
|
23 Mio. $
|
+2,84 Mio. $
|
+247.874
|
+16 %
|
|
|
18
|
Sector Gamma AS
Oslo,
Norway
|
17,5 Mio. $
|
+94.294 $
|
+8.239
|
+0,6 %
|
|
|
19
|
Asset Management One
Tokyo,
Japan
|
17,3 Mio. $
|
+3,65 Mio. $
|
+318.738
|
+30 %
|
|
|
20
|
T. Rowe Price Associates
Baltimore,
Maryland
|
14,9 Mio. $
|
-6,1 Mio. $
|
-532.621
|
-31 %
|
|
|
21
|
EcoR1 Capital
San Francisco,
California
|
13,8 Mio. $
|
+12,3 Mio. $
|
+1.074.600
|
Neu
|
|
|
22
|
Senzar Asset Management
New York
|
12 Mio. $
|
+10,7 Mio. $
|
+933.469
|
Neu
|
|
|
23
|
Tekla Capital Management
Boston,
Massachusetts
|
11,8 Mio. $
|
–
|
–
|
–
|
|
|
24
|
|
11,6 Mio. $
|
+5,07 Mio. $
|
+442.602
|
+96 %
|
|
|
25
|
|
11 Mio. $
|
+2,53 Mio. $
|
+220.932
|
+35 %
|
|
