|
1
|
Fidelity Investments
Boston,
Massachusetts
|
209 Mio. $
|
-2,5 Mio. $
|
-303.548
|
-1 %
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
195 Mio. $
|
+641.241 $
|
+77.746
|
+0,4 %
|
|
|
3
|
Janus Henderson Investors US
Denver,
Colorado
|
179 Mio. $
|
+6,2 Mio. $
|
+751.131
|
+4 %
|
|
|
4
|
|
126 Mio. $
|
+3,19 Mio. $
|
+386.856
|
+3 %
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
100 Mio. $
|
+2,83 Mio. $
|
+342.730
|
+3 %
|
|
|
6
|
T. Rowe Price Associates
Baltimore,
Maryland
|
73,4 Mio. $
|
+15,6 Mio. $
|
+1.895.117
|
+31 %
|
|
|
7
|
BlackRock Fund Advisors
San Francisco,
California
|
60,5 Mio. $
|
-406.490 $
|
-49.284
|
-0,7 %
|
|
|
8
|
Bridger Management
New York
|
56,7 Mio. $
|
+2,3 Mio. $
|
+279.437
|
+5 %
|
|
|
9
|
Consonance Capital Management
New York
|
54,1 Mio. $
|
+48,7 Mio. $
|
+5.903.302
|
Neu
|
|
|
10
|
Redmile Group
San Francisco,
California
|
47,3 Mio. $
|
+6,39 Mio. $
|
+774.724
|
+18 %
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
35,3 Mio. $
|
+89.119 $
|
+10.805
|
+0,3 %
|
|
|
12
|
State Street
Boston,
Massachusetts
|
33,3 Mio. $
|
-3,41 Mio. $
|
-413.761
|
-10 %
|
|
|
13
|
EverPoint Asset Management
Stamford,
Connecticut
|
29,6 Mio. $
|
+3,55 Mio. $
|
+429.840
|
+15 %
|
|
|
14
|
Sector Gamma AS
Oslo,
Norway
|
27,2 Mio. $
|
+5,05 Mio. $
|
+611.729
|
+26 %
|
|
|
15
|
State of Wisconsin Investment Board
Madison,
Wisconsin
|
26,5 Mio. $
|
-6,12 Mio. $
|
-742.416
|
-20 %
|
|
|
16
|
EcoR1 Capital
San Francisco,
California
|
22,6 Mio. $
|
+12,2 Mio. $
|
+1.480.424
|
+151 %
|
|
|
17
|
BVF Inc
San Francisco,
California
|
19,2 Mio. $
|
-11,6 Mio. $
|
-1.409.194
|
-40 %
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
18,9 Mio. $
|
+300.817 $
|
+36.472
|
+2 %
|
|
|
19
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
18 Mio. $
|
+1,28 Mio. $
|
+154.814
|
+9 %
|
|
|
20
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
17,8 Mio. $
|
-437.972 $
|
-53.101
|
-3 %
|
|
|
21
|
Credit Suisse
Zurich,
Switzerland
|
17,3 Mio. $
|
+1,18 Mio. $
|
+143.048
|
+8 %
|
|
|
22
|
Point72 Asset Management
Stamford,
Connecticut
|
12,9 Mio. $
|
-3,52 Mio. $
|
-426.736
|
-23 %
|
|
|
23
|
Geode Capital Management
Boston,
Massachusetts
|
10,2 Mio. $
|
+572.610 $
|
+69.425
|
+7 %
|
|
|
24
|
Adage Capital Partners
Boston,
Massachusetts
|
9,8 Mio. $
|
+8,86 Mio. $
|
+1.074.600
|
Neu
|
|
|
25
|
Asset Management One
Tokyo,
Japan
|
8,76 Mio. $
|
+104.847 $
|
+12.712
|
+1 %
|
|
