|
1
|
Fidelity Investments
Boston,
Massachusetts
|
US$ 209 mi
|
-US$ 2,5 mi
|
-303.548
|
-1%
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
US$ 195 mi
|
+US$ 641 mil
|
+77.746
|
+0,4%
|
|
|
3
|
Janus Henderson Investors US
Denver,
Colorado
|
US$ 179 mi
|
+US$ 6,2 mi
|
+751.131
|
+4%
|
|
|
4
|
|
US$ 126 mi
|
+US$ 3,19 mi
|
+386.856
|
+3%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
US$ 100 mi
|
+US$ 2,83 mi
|
+342.730
|
+3%
|
|
|
6
|
T. Rowe Price Associates
Baltimore,
Maryland
|
US$ 73,4 mi
|
+US$ 15,6 mi
|
+1.895.117
|
+31%
|
|
|
7
|
BlackRock Fund Advisors
San Francisco,
California
|
US$ 60,5 mi
|
-US$ 406 mil
|
-49.284
|
-0,7%
|
|
|
8
|
Bridger Management
New York
|
US$ 56,7 mi
|
+US$ 2,3 mi
|
+279.437
|
+5%
|
|
|
9
|
Consonance Capital Management
New York
|
US$ 54,1 mi
|
+US$ 48,7 mi
|
+5.903.302
|
Nova
|
|
|
10
|
Redmile Group
San Francisco,
California
|
US$ 47,3 mi
|
+US$ 6,39 mi
|
+774.724
|
+18%
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
US$ 35,3 mi
|
+US$ 89,1 mil
|
+10.805
|
+0,3%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
US$ 33,3 mi
|
-US$ 3,41 mi
|
-413.761
|
-10%
|
|
|
13
|
EverPoint Asset Management
Stamford,
Connecticut
|
US$ 29,6 mi
|
+US$ 3,55 mi
|
+429.840
|
+15%
|
|
|
14
|
Sector Gamma AS
Oslo,
Norway
|
US$ 27,2 mi
|
+US$ 5,05 mi
|
+611.729
|
+26%
|
|
|
15
|
State of Wisconsin Investment Board
Madison,
Wisconsin
|
US$ 26,5 mi
|
-US$ 6,12 mi
|
-742.416
|
-20%
|
|
|
16
|
EcoR1 Capital
San Francisco,
California
|
US$ 22,6 mi
|
+US$ 12,2 mi
|
+1.480.424
|
+151%
|
|
|
17
|
BVF Inc
San Francisco,
California
|
US$ 19,2 mi
|
-US$ 11,6 mi
|
-1.409.194
|
-40%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
US$ 18,9 mi
|
+US$ 301 mil
|
+36.472
|
+2%
|
|
|
19
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
US$ 18 mi
|
+US$ 1,28 mi
|
+154.814
|
+9%
|
|
|
20
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
US$ 17,8 mi
|
-US$ 438 mil
|
-53.101
|
-3%
|
|
|
21
|
Credit Suisse
Zurich,
Switzerland
|
US$ 17,3 mi
|
+US$ 1,18 mi
|
+143.048
|
+8%
|
|
|
22
|
Point72 Asset Management
Stamford,
Connecticut
|
US$ 12,9 mi
|
-US$ 3,52 mi
|
-426.736
|
-23%
|
|
|
23
|
Geode Capital Management
Boston,
Massachusetts
|
US$ 10,2 mi
|
+US$ 573 mil
|
+69.425
|
+7%
|
|
|
24
|
Adage Capital Partners
Boston,
Massachusetts
|
US$ 9,8 mi
|
+US$ 8,86 mi
|
+1.074.600
|
Nova
|
|
|
25
|
Asset Management One
Tokyo,
Japan
|
US$ 8,76 mi
|
+US$ 105 mil
|
+12.712
|
+1%
|
|
