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Ionis Pharmaceuticals

339 hedge funds and large institutions have $5.01B invested in Ionis Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 54 funds opening new positions, 102 increasing their positions, 122 reducing their positions, and 61 closing their positions.

New
Increased
Maintained
Reduced
Closed

more funds holding in top 10

Funds holding in top 10:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more ownership

Funds ownership:

less funds holding

Funds holding:

11% less capital invested

Capital invested by funds: $5.61B → $5.01B (-$606M)

11% less first-time investments, than exits

New positions opened: 54 | Existing positions closed: 61

16% less repeat investments, than reductions

Existing positions increased: 102 | Existing positions reduced: 122

Holders
339
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$24.8M
Puts
$18.8M
Net Calls
Net Calls Change

Top Buyers

1 +$79.4M
2 +$60.5M
3 +$57.7M
4
Citadel Advisors
Citadel Advisors
Florida
+$39.6M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$27.9M
Name Holding Trade Value Shares
Change
Change in
Stake
NWM
101
Nicola Wealth Management
British Columbia, Canada
$2.62M
Deutsche Bank
102
Deutsche Bank
Germany
$2.56M
Manulife (Manufacturers Life Insurance)
103
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.52M
JF
104
Jump Financial
Illinois
$2.45M
RPAM
105
Rhenman & Partners Asset Management
Sweden
$2.44M
New York State Common Retirement Fund
106
New York State Common Retirement Fund
New York
$2.36M
HSBC Holdings
107
HSBC Holdings
United Kingdom
$2.22M
Susquehanna International Group
108
Susquehanna International Group
Pennsylvania
$2.17M
Treasurer of the State of North Carolina
109
Treasurer of the State of North Carolina
North Carolina
$2.16M
SEI Investments
110
SEI Investments
Pennsylvania
$2.16M
GIP
111
Granite Investment Partners
California
$2.06M
Janus Henderson Group
112
Janus Henderson Group
United Kingdom
$1.99M
Simplex Trading
113
Simplex Trading
Illinois
$1.95M
SFM
114
Sphera Funds Management
Israel
$1.93M
VOYA Investment Management
115
VOYA Investment Management
Georgia
$1.92M
Lazard Asset Management
116
Lazard Asset Management
New York
$1.83M
State of New Jersey Common Pension Fund D
117
State of New Jersey Common Pension Fund D
New Jersey
$1.83M
APM
118
Avidity Partners Management
Texas
$1.81M
Skandinaviska Enskilda Banken (SEB)
119
Skandinaviska Enskilda Banken (SEB)
Sweden
$1.8M
Capital Fund Management (CFM)
120
Capital Fund Management (CFM)
France
$1.75M
PFSRSONJ
121
Police & Firemen's Retirement System of New Jersey
New Jersey
$1.74M
DC
122
Davenport & Co
Virginia
$1.7M
Ensign Peak Advisors
123
Ensign Peak Advisors
Utah
$1.66M
Jane Street
124
Jane Street
New York
$1.63M
EAM
125
Erste Asset Management
Austria
$1.6M