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Ionis Pharmaceuticals

360 hedge funds and large institutions have $6.67B invested in Ionis Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 81 funds opening new positions, 121 increasing their positions, 108 reducing their positions, and 58 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more funds holding in top 10

Funds holding in top 10:

more first-time investments, than exits

New positions opened: | Existing positions closed:

more capital invested

Capital invested by funds: $ → $

12% more repeat investments, than reductions

Existing positions increased: 121 | Existing positions reduced: 108

6% more funds holding

Funds holding: 339360 (+21)

1.77% more ownership

Funds ownership: 104.33%106.1% (+1.8%)

Holders
360
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
12
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$65.2M
Puts
$30M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
EDRH
76
Edmond de Rothschild Holding
Switzerland
$7.81M
Stifel Financial
77
Stifel Financial
Missouri
$7.76M
TAM
78
Tocqueville Asset Management
New York
$7.4M
SA
79
Sicart Associates
New York
$7.32M
RPAM
80
Rhenman & Partners Asset Management
Sweden
$7.19M
RhumbLine Advisers
81
RhumbLine Advisers
Massachusetts
$7.17M
BNP Paribas Financial Markets
82
BNP Paribas Financial Markets
France
$7.02M
SIMG
83
Sonora Investment Management Group
Arizona
$6.45M
Alyeska Investment Group
84
Alyeska Investment Group
Illinois
$6.28M
ACM
85
Aquatic Capital Management
Illinois
$6.25M
State Board of Administration of Florida Retirement System
86
State Board of Administration of Florida Retirement System
Florida
$6.08M
BBA
87
BLB&B Advisors
Pennsylvania
$5.99M
TCM
88
Tang Capital Management
California
$5.93M
Universal-Beteiligungs- und Servicegesellschaft
89
Universal-Beteiligungs- und Servicegesellschaft
Germany
$5.92M
ACM
90
ADAR1 Capital Management
Texas
$5.87M
JGC
91
J. Goldman & Co
New York
$5.83M
California State Teachers Retirement System (CalSTRS)
92
California State Teachers Retirement System (CalSTRS)
California
$5.73M
Rafferty Asset Management
93
Rafferty Asset Management
New York
$5.72M
Sumitomo Mitsui Trust Group
94
Sumitomo Mitsui Trust Group
Japan
$5.52M
NAMA
95
Nikko Asset Management Americas
New York
$5.52M
Squarepoint
96
Squarepoint
New York
$5.31M
KCM
97
Kennedy Capital Management
Missouri
$5.22M
TI
98
Trexquant Investment
Connecticut
$5.09M
EAM
99
Exome Asset Management
New York
$4.79M
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
100
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$4.58M