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Ionis Pharmaceuticals

339 hedge funds and large institutions have $5.01B invested in Ionis Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 54 funds opening new positions, 102 increasing their positions, 122 reducing their positions, and 61 closing their positions.

New
Increased
Maintained
Reduced
Closed

more funds holding in top 10

Funds holding in top 10:

more call options, than puts

Call options by funds: $ | Put options by funds: $

more ownership

Funds ownership:

less funds holding

Funds holding:

11% less capital invested

Capital invested by funds: $5.61B → $5.01B (-$606M)

11% less first-time investments, than exits

New positions opened: 54 | Existing positions closed: 61

16% less repeat investments, than reductions

Existing positions increased: 102 | Existing positions reduced: 122

Holders
339
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$24.8M
Puts
$18.8M
Net Calls
Net Calls Change

Top Buyers

1 +$79.4M
2 +$60.5M
3 +$57.7M
4
Citadel Advisors
Citadel Advisors
Florida
+$39.6M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$27.9M
Name Holding Trade Value Shares
Change
Change in
Stake
SFI
76
Susquehanna Fundamental Investments
Pennsylvania
$4.79M
ACM
77
Aquatic Capital Management
Illinois
$4.71M
SIMG
78
Sonora Investment Management Group
Arizona
$4.65M
Renaissance Technologies
79
Renaissance Technologies
New York
$4.63M
State Board of Administration of Florida Retirement System
80
State Board of Administration of Florida Retirement System
Florida
$4.6M
BBA
81
BLB&B Advisors
Pennsylvania
$4.59M
KCM
82
Kennedy Capital Management
Missouri
$4.54M
TCM
83
Tang Capital Management
California
$4.53M
Raymond James Financial
84
Raymond James Financial
Florida
$4.49M
Universal-Beteiligungs- und Servicegesellschaft
85
Universal-Beteiligungs- und Servicegesellschaft
Germany
$4.34M
Sumitomo Mitsui Trust Group
86
Sumitomo Mitsui Trust Group
Japan
$4.3M
NAMA
87
Nikko Asset Management Americas
New York
$4.3M
EAM
88
Exome Asset Management
New York
$4.09M
California State Teachers Retirement System (CalSTRS)
89
California State Teachers Retirement System (CalSTRS)
California
$3.99M
Connor, Clark & Lunn Investment Management (CC&L)
90
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$3.9M
EDRH
91
Edmond de Rothschild Holding
Switzerland
$3.75M
American Century Companies
92
American Century Companies
Missouri
$3.52M
State of Wisconsin Investment Board
93
State of Wisconsin Investment Board
Wisconsin
$3.27M
Neuberger Berman Group
94
Neuberger Berman Group
New York
$3.09M
AllianceBernstein
95
AllianceBernstein
Tennessee
$3.04M
PP
96
PDT Partners
New York
$2.9M
DekaBank Deutsche Girozentrale
97
DekaBank Deutsche Girozentrale
Germany
$2.87M
DA
98
DCF Advisers
Connecticut
$2.87M
Walleye Capital
99
Walleye Capital
New York
$2.87M
UOC
100
UBS O'Connor
Illinois
$2.74M