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Ionis Pharmaceuticals

354 hedge funds and large institutions have $5.61B invested in Ionis Pharmaceuticals in 2024 Q4 according to their latest regulatory filings, with 58 funds opening new positions, 119 increasing their positions, 120 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

16% more first-time investments, than exits

New positions opened: 58 | Existing positions closed: 50

1.72% more ownership

Funds ownership: 99.9%101.62% (+1.7%)

0% more funds holding

Funds holding: 353354 (+1)

1% less repeat investments, than reductions

Existing positions increased: 119 | Existing positions reduced: 120

11% less capital invested

Capital invested by funds: $6.3B → $5.61B (-$692M)

15% less call options, than puts

Call options by funds: $26.1M | Put options by funds: $30.5M

Holders
354
Holders Change
+1
Holders Change %
+0.28%
% of All Funds
4.66%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
58
Increased
119
Reduced
120
Closed
50
Calls
$26.1M
Puts
$30.5M
Net Calls
-$4.46M
Net Calls Change
-$17.6M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
51
Baker Bros. Advisors
New York
$12.5M +$5.03M +134,445 +60%
Nomura Holdings
52
Nomura Holdings
Japan
$12.5M -$3.58M -95,814 -21%
TAM
53
Tocqueville Asset Management
New York
$12.3M -$2.05M -54,730 -13%
Wells Fargo
54
Wells Fargo
California
$11.6M -$417K -11,145 -3%
Voloridge Investment Management
55
Voloridge Investment Management
Florida
$11.1M -$2.38M -63,698 -17%
Bank of Montreal
56
Bank of Montreal
Ontario, Canada
$10.9M +$3.67M +98,263 +46%
N
57
Nuveen
North Carolina
$10.2M -$517K -13,825 -5%
Manulife (Manufacturers Life Insurance)
58
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$10M -$847K -22,668 -7%
Jacobs Levy Equity Management
59
Jacobs Levy Equity Management
New Jersey
$9.85M -$13.8M -368,966 -57%
Swiss National Bank
60
Swiss National Bank
Switzerland
$9.76M +$845K +22,600 +9%
Adage Capital Partners
61
Adage Capital Partners
Massachusetts
$9.61M -$8.41M -225,000 -45%
PFM
62
Privium Fund Management
Netherlands
$9.33M +$600K +16,050 +6%
BNP Paribas Financial Markets
63
BNP Paribas Financial Markets
France
$8.9M +$2.96M +79,193 +45%
Artisan Partners
64
Artisan Partners
Wisconsin
$8.83M -$74.3M -1,987,820 -89%
SL
65
Siren LLC
Connecticut
$8.74M
Corient Private Wealth
66
Corient Private Wealth
Florida
$8.36M +$78K +2,087 +0.9%
Rafferty Asset Management
67
Rafferty Asset Management
New York
$8.3M +$1.44M +38,578 +19%
SGA
68
Sector Gamma AS
Norway
$8.25M +$934K +25,000 +12%
ACM
69
Aquatic Capital Management
Illinois
$8.04M +$8.6M +230,016 New
KCM
70
Kennedy Capital Management
Missouri
$7.81M +$2.29M +61,202 +38%
OIC
71
Orion Investment Company
Missouri
$7.55M -$94.4K -2,525 -1%
EP
72
Eversept Partners
New York
$7.51M -$9.58M -256,403 -54%
SFI
73
Susquehanna Fundamental Investments
Pennsylvania
$7.45M +$7.96M +213,015 New
RPAM
74
Rhenman & Partners Asset Management
Sweden
$7.43M +$654K +17,500 +9%
Stifel Financial
75
Stifel Financial
Missouri
$7.39M +$1.08M +28,988 +16%

IONS Hedge Fund Activity: Q4 2024 in Review

354 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Ionis Pharmaceuticals (IONS) for Q4 2024, worth a combined $5.61B — down 11% from $6.3B a quarter earlier.

Buyers outnumbered sellers: 58 funds opened new IONS positions and 50 closed out — a net gain of 8 holders — while 119 added to existing stakes and 120 trimmed.

The largest buyer was Capital World Investors, adding an estimated $136M. The largest seller was Artisan Partners, cutting an estimated $74.3M.

  • 354 institutional investors held Ionis Pharmaceuticals (IONS) as of Q4 2024, up from 353 in Q3 2024.
  • Funds reported $5.61B of Ionis Pharmaceuticals stock for Q4 2024, down 11% quarter-over-quarter.
  • 58 funds opened new Ionis Pharmaceuticals positions in Q4 2024 and 50 closed out, a net change of +8 holders.
  • The largest Ionis Pharmaceuticals buyer in Q4 2024 was Capital World Investors, an estimated $136M added.
  • The largest Ionis Pharmaceuticals seller in Q4 2024 was Artisan Partners, an estimated $74.3M sold.

Based on aggregated 13F filings for Q4 2024.