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516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Teacher Retirement System of Texas
201
Teacher Retirement System of Texas
Texas
$4.93M +$255K +3,330 +7%
Handelsbanken Fonder
202
Handelsbanken Fonder
Sweden
$4.84M -$84.1K -1,100 -2%
ABG
203
Ally Bridge Group
New York
$4.8M -$2.86M -37,400 -44%
First Trust Advisors
204
First Trust Advisors
Illinois
$4.77M +$1.62M +21,176 +81%
CFM
205
Catalyst Funds Management
Australia
$4.75M +$3.61M +47,175 New
EAM
206
Erste Asset Management
Austria
$4.74M
HCA
207
Harbor Capital Advisors
Illinois
$4.71M -$1.99M -26,030 -36%
Truist Financial
208
Truist Financial
North Carolina
$4.68M +$108K +1,409 +3%
Canada Life
209
Canada Life
Manitoba, Canada
$4.66M +$290K +3,792 +9%
TRCT
210
Tower Research Capital (TRC)
New York
$4.55M +$2.89M +37,820 +510%
BCI
211
Brinker Capital Investments
Pennsylvania
$4.21M +$236K +3,082 +8%
GC
212
Guggenheim Capital
Illinois
$4.17M +$455K +5,945 +17%
MIM
213
Monashee Investment Management
Massachusetts
$4.03M +$3.06M +40,000 New
Pathstone Holdings
214
Pathstone Holdings
New Jersey
$3.89M -$528K -6,906 -15%
KK
215
KLP Kapitalforvaltning
Norway
$3.8M +$275K +3,600 +11%
ACP
216
Acuta Capital Partners
California
$3.73M -$5.28M -69,004 -65%
BAMCO Inc
217
BAMCO Inc
New York
$3.69M -$1.78M -23,300 -39%
NRD
218
Nebula Research & Development
New York
$3.69M +$2.54M +33,282 +985%
CUAMC
219
China Universal Asset Management Company
China
$3.68M +$21.2K +277 +0.8%
LCM
220
Legato Capital Management
California
$3.63M -$442K -5,778 -14%
Natixis Advisors
221
Natixis Advisors
Massachusetts
$3.57M +$428K +5,597 +19%
ORI
222
Oak Ridge Investments
Illinois
$3.44M -$593K -7,757 -18%
CCM
223
Cinctive Capital Management
New York
$3.31M +$713K +9,321 +40%
AssetMark Inc
224
AssetMark Inc
California
$3.23M +$451K +5,892 +22%
MA
225
MYDA Advisors
New York
$3.22M +$1.84M +24,000 +300%

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.