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516 hedge funds and large institutions have $21.2B invested in Insmed in 2025 Q2 according to their latest regulatory filings, with 131 funds opening new positions, 165 increasing their positions, 189 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

152% more first-time investments, than exits

New positions opened: 131 | Existing positions closed: 52

38% more capital invested

Capital invested by funds: $15.3B → $21.2B (+$5.85B)

17% more funds holding

Funds holding: 441516 (+75)

6% more funds holding in top 10

Funds holding in top 10: 3133 (+2)

5.23% more ownership

Funds ownership: 110.29%115.51% (+5.2%)

13% less repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 189

16% less call options, than puts

Call options by funds: $300M | Put options by funds: $356M

Holders
516
Holders Change
+75
Holders Change %
+17.01%
% of All Funds
6.79%
Holding in Top 10
33
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+6.45%
% of All Funds
0.43%
New
131
Increased
165
Reduced
189
Closed
52
Calls
$300M
Puts
$356M
Net Calls
-$56.3M
Net Calls Change
+$15.7M
Name Holding Trade Value Shares
Change
Change in
Stake
PHK
176
Point72 Hong Kong
Hong Kong
$7.03M +$5.34M +69,814 New
LP
177
LMR Partners
United Kingdom
$6.94M +$2.45M +32,072 +87%
PFSRSONJ
178
Police & Firemen's Retirement System of New Jersey
New Jersey
$6.83M +$2.36M +30,803 +83%
EIM
179
Essex Investment Management
Massachusetts
$6.68M -$34.8K -455 -0.7%
State of New Jersey Common Pension Fund D
180
State of New Jersey Common Pension Fund D
New Jersey
$6.45M +$384K +5,027 +9%
EAM
181
EFG Asset Management
Oregon
$6.39M -$2.35M -30,696 -33%
FLAM
182
First Light Asset Management
Minnesota
$6.33M -$402K -5,252 -8%
SC
183
Stempoint Capital
New York
$6.2M -$1.95M -25,481 -29%
AI
184
Axiom Investors
Connecticut
$6.11M -$1.47M -19,184 -24%
EI
185
EAM Investors
California
$6.03M -$899K -11,758 -16%
APM
186
Avidity Partners Management
Texas
$5.94M -$3.67M -48,000 -45%
XT
187
XTX Topco
Cayman Islands
$5.67M +$2.69M +35,130 +165%
Ohio Public Employees Retirement System (OPERS)
188
Ohio Public Employees Retirement System (OPERS)
Ohio
$5.58M +$4.24M +55,425 New
VF
189
Virtu Financial
New York
$5.46M +$4.15M +54,302 New
Stifel Financial
190
Stifel Financial
Missouri
$5.43M +$1.43M +18,765 +53%
TIM
191
Thornburg Investment Management
New Mexico
$5.36M -$1.19M -15,592 -23%
NL
192
NWAM LLC
Washington
$5.35M -$300K -3,929 -7%
ASRS
193
Arizona State Retirement System
Arizona
$5.34M +$333K +4,355 +9%
BFM
194
Boothbay Fund Management
New York
$5.31M +$2.17M +28,336 +116%
Zurich Cantonal Bank
195
Zurich Cantonal Bank
Switzerland
$5.18M +$604K +7,893 +18%
EGI
196
EAM Global Investors
California
$5.05M -$864K -11,302 -18%
AQR Capital Management
197
AQR Capital Management
Connecticut
$5M -$117K -1,524 -3%
HIM
198
Hillsdale Investment Management
Ontario, Canada
$5M -$168K -2,200 -4%
DekaBank Deutsche Girozentrale
199
DekaBank Deutsche Girozentrale
Germany
$4.96M
MML Investors Services
200
MML Investors Services
Massachusetts
$4.93M +$1.36M +17,809 +57%

INSM Hedge Fund Activity: Q2 2025 in Review

516 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Insmed (INSM) for Q2 2025, worth a combined $21.2B — up 38% from $15.3B a quarter earlier.

Buyers outnumbered sellers: 131 funds opened new INSM positions and 52 closed out — a net gain of 79 holders — while 165 added to existing stakes and 189 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $710M. The largest seller was BlackRock, cutting an estimated $375M.

  • 516 institutional investors held Insmed (INSM) as of Q2 2025, up from 441 in Q1 2025.
  • Funds reported $21.2B of Insmed stock for Q2 2025, up 38% quarter-over-quarter.
  • 131 funds opened new Insmed positions in Q2 2025 and 52 closed out, a net change of +79 holders.
  • The largest Insmed buyer in Q2 2025 was JP Morgan Chase, an estimated $710M added.
  • The largest Insmed seller in Q2 2025 was BlackRock, an estimated $375M sold.

Based on aggregated 13F filings for Q2 2025.